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A SINGLE-CENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED CROSSOVER PILOT STUDY WITH TRAMADOL TO VALIDATE TWO EXPERIMENTAL HUMAN PAIN MODELS AT THE KENDLE CLINICAL PHARMACOLOGY UNIT

To evaluate and implement the cutaneous electrical stimulation pain model at the Kendle Clinical Pharmacology Unit.To investigate whether these human experimental pain models can discriminate the analgesic effects of a single oral dose of Tramadol…