15 results
Objectives: 1. To assess the prevalence of pain in elderly with dementia and to study the relationship between the various subtypes of dementia and the presence of specific types of pain(e.g. nociceptive pain, neuropathic pain, and orofacial pain).…
In the current study we want to further explore the predictability of pre-treatment pain variability on the probability to experience pain relief. Knowledge on the understanding of individual differences in analgesic properties of a drug is of…
To assess the analgesic efficacy, safety, and tolerability of once daily orally administered cebranopadol in a total of 3 fixed doses (100 µg, 300 µg, and 600 µg cebranopadol) compared to placebo in subjects with moderate to severe chronic pain due…
The aim of the research is to study the effectiveness of PRF treatment on radicular neuropathic pain. The effectiveness will be determined by eQST, VAS and RAND-36 values. To evaluate the effectiveness of the PRF treatment, there will be included a…
The main objective of this study is to provide insight in the morbidity with regards to the upper extremity surrounding the radial access route in percutaneous coronary interventions.Secondary objectives are the following:• To provide insight at the…
By means of the administration of a visual search task, an associative learning task, and an antisaccade task, we aim to resolve the primary research question whether a painful hand (more than a non-painful hand) positioned nearby a visual stimulus…
ARA290 is a new drug against neuropathic pain and was succesfully tested in previous studies on patients with neuropathic pain due to diabetes and sarcoidosis. The current study involves sarcoidosis patients with pain due to neuropathy. The purpose…
(1) To assess the effect of deafferentation on pain processing in the brain by task-fMRI(2) To assess the effect of deafferentation on reaction time (sedation) by task-fMRI(3) To assess the effect of deafferentation on endogenous pain modulation
As none of the proposed experimental conditions have been executed with chronic pain patients, our main objective is to determine the sensitivity of the experimental conditions. Besides, we investigate the attention-bias for pain signals that…
First, we investigate the attention-bias for pain signals that chronic pain patients (CPP) are suggested to have. Second, we investigate whether the chronicity of pain is related to faster learning and slower *unlearning* of new associations between…
To determine whether the ulnar nerve*s cross-sectional area decreases over time after endoscopic in situ neurolysis, and whether this correlates with electrophysiological findings.
1) The primary objective of this pilot study is to compare the clonal composition of the TCR repertoire in anterior fascicular sural nerve biopsies with the TCR repertoire in peripheral blood of CIDP patients with active disease in order to identify…
The aim of this study is to test the hypothesis that a combination of optimized intravenous pain therapy and continuous sciatic nerve block decreases the point prevalence of phantom limb pain 12 months after transtibial amputation for peripheral…
Study Rationale and ObjectivesThe objective of the study is to determine the efficacy and safety of lacosamide, a sodium channel blocker, in patients with pain due to SCN9A-associated SFN. The proposed study plans to recruit patients with clinically…
1.The first objective is to determine the nature and spatial distribution of sonographic abnormalities in demyelinating and axonal polyneuropathies of different etiologies. 2.On the basis of the findings in objective 1, we define a standardized HRUS…