223 results
Does mindfulness based cognitive therapy in addition to treatment as usual (TAU) improve QoL compared to TAU alone in patients with CPP based on a hypertonic pelvic floor ?
Assessing the effects of SCS in patients with mononeuropathy measured according to the IMMPACT guidelines (pain reduction, improvement of quality of life, physical and emotional functioning, medication use, adverse events), and assessing the…
The goal of the stomp trial will be to investigate the effectiveness of both the neurolysis and neurectomy procedure in patients with persistent symptoms of meralgia paresthetica. In addition, in this trial we want to determine to what extend…
The primary objective of this Randomised Controlled Trial (RCT) is to evaluate the efficacy of DRG stimulation with the Axium® SCS system as compared to CMM in terms of pain relief. Efficacy will be assessed by comparing the percentage of subjects…
The aim of this explorative study is to lay the foundation for investigating the carryover effects in spinal cord stimulation.
Primary Objective:To evaluate the efficacy of VX-150 for the treatment of pain caused by small fiber neuropathy.Secondary Objectives:* To evaluate the safety and tolerability of VX-150* To evaluate the pharmacokinetics (PK) of VRT-1207355 and the…
Image with magneto-encephalography (MEG) the supraspinal effects of conventional and burst SCS settings in patients who already have a spinal cord stimulator, to study the analgesic mechanisms of action of SCS and to improve the treatment of chronic…
The aim of this study is to provide reference values for peptidergic and non peptidergic intra-epidermal nerve fiber density of the hand and distal leg. Furthermore, we will compare the intra-epidermal nerve fiber density of three biopsy sites of…
Primary Objectives: To describe the morphology of the carpal tunnel and median nerve 6 months after primary carpal tunnel release using ultrasonography and the electrophysiological properties of the median nerve as found by nerve conduction studies…
To investigate the effects of the cognitive behavioural intervention GEXP on physical activity and quality of life, hereby targeting specific fears in patients with PDN.Hypothesis: GEXP, as addition to usual care, increases the levels of physical…
1.The first objective is to determine the nature and spatial distribution of sonographic abnormalities in demyelinating and axonal polyneuropathies of different etiologies. 2.On the basis of the findings in objective 1, we define a standardized HRUS…
To determine whether a second IVIg course in GBS patients with a poor prognosis improves functional outcome after 4 weeks.
To validate the results from two RCTs that SCS is indeed capable of treating otherwise refractory diabetic neuropathic pain, and to evaluate the effects of burst stimulation settings in this patient group.
This protocol is aimed at investigating three research questions related to innate immunity in GBS:1. Do patients with viral GBS have a different innate response to microbial triggers compared to healthy controls?2. Do patients with recurrent GBS…
Objectives: 1. The first objective is to determine the nature and spatial distribution of sonographic abnormalities in CIAP and in CIDP, MIDN and MMN. 2. On the basis of the findings in objective 1, we will define a standardized HRUS research…
The primary objective of this study is to determine the efficacy of a predefined vitamin D dosing regimen on the prevalence of vitamin D insufficiency in MM patients. Secondary objectives are to detect the influence of several variables (age, gender…
The primary goal of this pilot is to study the chronic pain patient population with respect to the prevalence of central sensitization measured with eQST measurements.
The main objective is to describe in detail the variation in clinical subtypes, clinical course, past and current practice of treatment, antibody titers, and clinical picture of IgM monoclonal gammopathy associated polyneuropathy at the various…
The primary objective of this study is to determine the correlation between the 25-hydroxyvitamin D serum levels and PN in patients with multiple myeloma.
Our primary objective is to determine the prevalence of neuropathic pain within one-year ICU survivors. A secondary objective is to compare patient and disease characteristics between patients reporting neuropathic versus other pain, in order to…