223 results
A: The purpose of the current trial is to investigate what is the best treatment for patients with clinical definite CTS and normal nerve conduction studies and to see what is the value of ultrasonography in this specific group of patients.B: The…
The aim of the study is to describe the incidence and characteristics of CRPS in the Dutch population. Also will be investigated which factor are associated with the ocurrence of the disease.
1. The objective of this study is to aquire knowledge about the development of reactive hyperaemia and inflammatory responses of the skin after shear- force and pressure loading. We want to investigate if patients with diabetes type 2 will develop…
Primary: to develop and validate a clinical prediction rule to predict a favourable or unfavourable disease course for NP patients, therewith enabling tailor made treatments for NP patients.Secondary: determine prevalence of clinical signs of NP in…
The aim of this study is to test the hypothesis that a combination of optimized intravenous pain therapy and continuous sciatic nerve block decreases the point prevalence of phantom limb pain 12 months after transtibial amputation for peripheral…
The primary objective is:1. To investigate whether high frequency low dosage IVIg treatment is more effective than low frequency high dosage as maintenance treatment for CIDP. Secondary objectives are:2. To investigate whether high frequency low…
Study Rationale and ObjectivesThe objective of the study is to determine the efficacy and safety of lacosamide, a sodium channel blocker, in patients with pain due to SCN9A-associated SFN. The proposed study plans to recruit patients with clinically…
Primary Objective: to assess formally the responsiveness of a core set of measures derived from the previous CI-PeriNoms Study (Cavaletti, et al., 2013).Secondary objective: to test the responsiveness of the CIPN specific Rasch-built Overall…
Given the significant number of patients with OIPN and the possible prophylactic properties of venlafaxine, this study is designed. This study will consist of a randomised placebo-controlled clinical trial to study the prophylactic effect of…
We purpose to determine whether the international normative values are applicable in our center in 10 healthy participants. Furthermore, CCM will be introduced as additional diagnostic tool in patients with (possible) SFN.
Primary Objective: To study whether nocturnal symptoms of CTS depend on wrist position and, if so, on which position. Identifying which wrist position aggravates CTS could help design a more effective splint. Secondary Objective: To study whether…
Primary objective is to study the number of patients gaining at least 50% pain reduction within 8 weeks following PRF as compared to following a neurectomy. Pain intensity will be measured using numeric pain rating score (NPRS, 0-10) and Verbal…
Molecular genetic testing for SEPT9 mutations is clinically available, but is not of much added value, at least in the Netherlands because of the low prevalence of SEPT9 mutations observed in Dutch HNA patients. Objective 1: To identify with WES de…
This mapping study will contribute to our understanding of the pathogenesis of ACNES and the complex anatomical distribution of sensory input of the trunk. It will also pave the way for a better diagnostic work-up, allowing for better surgical…
This study aims to develop a prediction rule for PMPS one year after breast surgery based on neurophysiological, psychological, and clinical parameters. Based on this prediction, individualized perioperative management and postoperative revalidation…
To estimate the frequency/ prevalence of acute or active HEV infection in patients presenting with (sub)acute post-infectious and/or immune-mediated neurological illness like neuralgic amyotrophy, (idiopathic) Guillain Barre syndrome, idiopathic…
To assess the change in excitability parameters induced by IVIG infusion. This will be achieved by comparing excitability-parameters between the time of maximal weakness (just before the next IVIG infusion) and the time of maximal clinical…
The aim is to investigate static and dynamic tissue oxygenation state and skin temperature in patients with CRPS-I and to compare CRPS-I patients with pain patients and healthy controls. The correlation between tissue oxygenation, skin temperature…
To study the long term effects of decompression surgery of lower extremity nerves on pain, sensation and incidence of ulcers andamputations.
We aim to investigate the amount of patients who have lasting benefit from such surgery, and which proportion eventually get recurrent symptoms. We are going to investigate the cohort which has previously been studied by our group (protocol Dr.…