223 results
Evaluation of the (cost-)effectiveness of surgical decompression of compressed lower extremity nerves (LEND surgery) compared to patients 'treated' with conventional best care.
To study the neuroplasticity of the brain due to facial synkinesis by assessing the somatotopy of the face on several cortexes of interest (primary and secondary somatosensory cortexes, the primary motor cortex, the supplementary motor cortex, the…
To evaluate the effect of peripheral nerve decompression surgery in patients with headache caused by entrapment neuropathy,comparing it to conventional treatment.
Primary Objective- To evaluate the feasibility and test-retest variability of nerve excitability threshold tracking - To investigate the sensitivity of nerve excitability measures to detect the effects of mexiletine- To investigate the sensitivity…
The main objective of this study is to compare upper extremity dysfunction following slender TRPCI using small bore catheters (*5F) compared to standard PCI using regular size guiding catheters(*6F) and conventional stent techniques. Secondary…
Primary:To determine the efficacy of AG10 in the treatment of subjects with symptomatic transthyretin amyloid polyneuropathy (ATTR-PN) by evaluating the difference between the AG10 and placebo groups in Modified Neuropathy Impairment Score + 7 (mNIS…
The objective of this study is to investigate if low frequency stimulation with a DRG stimulator effects peripheral blood blow in patients with CRPS and vasomotor disturbances. The secondary goal is to investigate if the frequency with the best…
The primary objective is to investigate if there is altered mitochondrial oxygenation and consumption in the skin cells of the affected extremity in patients with CRPS by measuring the mitoPO2 and mitoVO2.
The International GBS Outcome Study (IGOS) aims to identify the most important clinical and biological determinants of disease progression and recovery in GBS. This information will be used to understand the diversity in clinical presentation and…
To explore whether patients with SCN9A-associated SFN have an abnormal brain activation pattern on resting state fMRI and altered structural connectivity on DTI versus age- and gender-matched healthy controls. With this knowledge, objective pain…
In this pilot study we want to investigate if 3D ultrasound can adequately visualize long nerve tracts and if 3D reconstructions of nerves and volumetric measurements can be made with this technique. If this is the case, this could not only decrease…
To demonstrate that SCS is capable of treating otherwise refractory neuropathic pain after chemotherapy / radiotherapy.
Primary objective: To evaluate the efficacy of IVIg treatment (4 courses of treatment, 3 weeks apart) compared to placebo on pain alleviation. Secondary objectives: 1. Pain intensity, pain qualities, and other SFN related complaints, daily and…
Evaluate the effect of the adjustable rocker, the self-adjusting insole, and a combination of both on in-shoe plantar peak pressures in patients with diabetes related neuropathy.
Primary objective of this randomized controlled trial is to assess whether combining IVIg and IVMP leads to more frequent long-term remission in CIDP compared to treatment with IVIg alone. Main secondary objectives are to assess whether IVIg and…
To determine if SCS and/or DRGS is can influence the perception of experimentally induced pruritus.
Primary objective is to define and validate a patient perceived minimal clinical important difference (pMCID) on a linear disability scale. Secondary objectives are to determine whether pMCID during improvement is larger compared to the pMCID during…
1. To investigate whether the Aeonose* is able to distinguish (1) patients with CRPS from patients with CTS (2) patients with CRPS from healthy controls (3) patient with CTS from healthy controls based on volatile organic compounds in the exhaled…
What is the long-term prognosis in patients with an ulnar neuropathy at the elbow and a motor conduction block of >= 50%?
To assess the range and strength of dorsiflexion of the ankle and the percentage of AFO-use after executing a variation on the circumtibial route of the posterior tibial tendon transfer, performed in our center on patients with foot drop.