67 results
To identify novel (causal) risk factors, including biomarkers and genetic determinants for disease progression and (severe) diabetes complications in people with T2D, in order to develop new, more targeted and effective therapies that will improve…
The objective of this study is to identify clinical and non-invasive neuroimaging markers that are characteristic for RBD in PD and DLB.
This study comprises a first proof of concept. The primary aim is to investigate the effect of a ketogenic diet on EDS and sustained attention in adult NT1 patients. Secondary aims are to investigate if a ketogenic diet improves weight reduction,…
The primary objective is to assess the role of obstructive sleep apnea related pathophysiological mechanisms in the initiation of atrial fibrillation by a multi-parametric strategy that combines the estimated parameters. The main hypothesis is that…
This study aims to assess the safety and efficacy of the remed*® system in adult patients with moderate to severe central sleep apnea in real life.
The aim of this longitudinal study is to find new biological, clinical and/or electrophysiological biomarkers in order to define and differentiate individual diagnoses of NT1 and the NBL, and to find improved treatment targets and strategies.
Primary objective:To assess whether hydralazine in combination with valproate is effective in treating the symptoms of narcolepsy.Secondary objectives:- To assess the safety of treating NT1 patients with hydralazine in combination with valproate.-…