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The post-illumination pupil respOnse and its relation with Sleep quality and skin temperature in patients with a history of optic Chiasm Compression

Our main objective is to assess the difference in PIPR after a blue-light stimulus between hypopituitarism patients with and without a history of CC. Secondary objectives include differences in subjective and objective sleep quality, sleep-wake…

Unravelling the sleepy brain: A neuroimaging study in central hypersomnolence disorders

The objective is to identify non-invasive neuroimaging biomarkers and mechanisms characterizing different phenotypes of central disorders of hypersomnolence (narcolepsy type 1, narcolepsy type 2 and idiopathic hypersomnia) as compared to groups of…

Mass cytometry-based analysis of the composition of the immune system in peripheral blood and cerebrospinal fluid in narcolepsy

Achieving more detailed information about the possible auto-immune process that underlies narcolepsy by:(1) Assessing differences in immune composition between peripheral blood samples of healthy controls (n=30) and type 1 narcolepsy patients (n=30…

Randomised controlled trial of the effects of cognitive behavioral therapy for insomnia on sleep, impulsivity and aggression in forensic psychiatric patients

Evaluating the effects of cognitive behavioral therapy for chronic insomnia (CBT-I) on sleep, general psychopathology, impulsivity and aggression in forensic psychiatric patients.