99 results
The primary objective of this study is to assess whether motor learning using external attentional focus instructions results in superior single-task motor performance, movement automaticity, and dual-task performance in inpatient stroke patients…
To evaluate the effects of tDCS on information processing speed in comparison to sham tDCS in patients after stroke with ascertained reduced processing speed. A proof of principle study.
1) Is e-COGRAT usable within the ABI population?2) What are the patients* experiences with e-COGRAT?3) What are the therapists* experiences with e-COGRAT?4) What changes in the e-COGRAT are necessary?5) Does this pilot with e-COGRAT show a decline…
The main objective of this study is to find (epi)genetic markers including SNPs/haplotypes, DNA methylation and RNA expression correlating with cognitive decline in clinical patients with Mild Cognitive Impairment (MCI) and Subjective Cognitive…
To study the longitudinal dynamics of blood biomarkers, including NfL, in patients with frontotemporal dementia.
To determine the relative bioavailability of pramipexole 4.5 mg tablets vs. 4.5 mg Sifrol in healthy subjects after up-titration.
To report on (the age-dependency of) the long-term effect(s) of chronic SSRI treatment during adolescence or adulthood on the outgrowth and function of the 5-HT system, using state-of-the-art Magnetic Resonance Imaging (MRI) techniques and other,…
The present study will examine how young-onset-dementia patients and their families can be supported in their home environment as long as possible and institutionalisation can be delayed. For this the functioning and care needs of young-onset-…
Primary Objective: Our main goal is to contribute to the identification of an attentional profile of the paediatric TBI population, by analysing the quality and efficiency of alerting, orienting, executive and sustained attentional functioning. This…
The purpose of this study is to examine whether walking ability and plantar flexor strength of young children with CP who follow functional power training improve more compared to usual care.
2.1 Primary Objectives• Evaluate the safety and tolerability of 2 fixed doses of FRM-0334 (300 and 500 mg daily in 2 sequential periods) over 28 days in subjects with prodromal to moderate FTD-GRN• Assess the PD effects of FRM-0334 on the change…
The objective is to assess the intra-subject reliability of tDCS induced effects on the reaction time in the lower extremities of healthy subjects.
1) To determine if microinfarcts can be detected in the brain with 7T MRI in AD patients2) To determine the prevalence and number of cerebral microbleeds on 7T MRI in patients with AD and to relate these lesions to cognition and to the vascular risk…
Primary objective of the study: 1. To report on the age-dependency of the effect(s) of MPH or SSRI treatment on the outgrowth of the DA and 5-HT systems, respectively, using state-of-the-art Magnetic Resonance Imaging (MRI) techniques
What are the long-term consequences of prenatal exposure to cannabis and nicotine on the brain development of 6-year old children?
The main objective of this study is to characterize the flow of information in the fronto-parietal network during the simulation of movements using intracranial EEG recordings. In the characterization we will pinpoint the neuronal (sub)regions of…
To investigate the treatment effect of the protocol Treatment of deficits in Emotion, Social Cognition and behaviour regulation (T-ScEMO) after traumatic brain injury.
* To implement a standardised MRI acquisition protocol in multiple centres across Europe (Part A).* To identify and evaluate new biomarkers of disease progression in patients with amnestic MCI by collecting biochemical, neuroimaging,…
The primary objective is to evaluate the presence of brain damage (defined by white matter lesions (WMLs) or cerebral atrophy or deviations at neuropsychological examination (NPE)) among adults with tetralogy of Fallot (TOF). The secondary objective…
The main, primary objective of this study is identification of the molecular mechanisms that regulate structure and function of red blood cells in patients with neurodegeneration accompanied by the presence of abnormal red blood cells (…