14 results
The primary objective is to obtain OCT data for children aged 4 to 10 diagnosed with non-syndromic craniosynostosis and to compare these to the normal reference values.
To establish normal ranges for the lateral ventricles in neonates with a gestational age ranging from 25 to 42 weeks.
The Eurotherm3235trial will examine the relationship between ICP reduction after TBI using therapeutichypothermia and patient outcome.
Obtain normal values of ventricle volumes and CSF circulation in healthy volunteers with MRI scanning.
To determine the mean systemic filling pressure, the arm-occlusion pressure, the cerebral zero flow pressure and their response to changes in volume status and vasoactive medication. To evaluate and confirm the value of mean systemic filling…
1. Is the concentration of brain specific proteins in CSF higher in newborn who are treated after high threshold as compared to newborns who are treated after low threshold?2. Is there any relationship between the concentration of brain specific…
Primary Objective To measure the agreement between ICP (through Headsense monitor) and lumbar CSF pressure (through a lumbar puncture).
The objective of the study is to set up and validate a digital neurotraumatology quality registry, to identify the most effective clinical care and to provide high quality evidence in support of treatment recommendations and guidelines.
This study has been transitioned to CTIS with ID 2024-514488-24-01 check the CTIS register for the current data. Primary Objective: To determine the safety and efficacy of 6000 IU Cinryze in patients with moderate and severe TBI (GCS <13 with…
The aim of this PMCF study is to confirm the clinical safety and performance aspects of intracranial catheter placements forthe medical indications, hydrocephalus of any origin or ICP elevation. The study design requires determination of…
In a phase II study we will evaluate safety and proof-of-concept of acetazolamide in patients with aneurysmal SAH. The primary aim of this study is to evaluate whether acetazolamide improves cerebral perfusion as measured with magnetic resonance…
Main aim: We will assess whether the new intervention protocol provides a greater percentage of time during which CPP is within 5 mmHg of calculated individual and flexible CPP (CPPopt). This window has been chosen based on past studies which show…
The primary objective of this study is to determine the effect of changes in transpulmonary pressure on ICP in severe TBI patients. Secondary objectives are to study the effect of change in transpulmonary pressure on cerebral blood flow velocity,…
Our global aims are * To improve characterization and classification of TBI in Europe, with inclusion of emerging technologies.* To identify the most effective clinical care and to provide high quality evidence in support of treatment…