5299 results
The primary efficacy objectives of this two-cohort study are:o To demonstrate that ZX008 is superior to placebo as adjunctive therapy in the treatment of symptoms of Dravet syndrome in children and young adults based on change in the frequency of…
To investigate: (1) the difference in degrees between a Cobb angle measured in supine position and standing position with standard instructions of the radiographer (main objective)(2) the correlation between the Cobb angle in both supine position…
In this project we aim to anticipate the need for effective interventions and develop an outreaching systemic intervention for promoting adherence and self-management among adolescent and adult kidney transplant recipients aged from 12 years. The…
With this study we aim to investigate the occurrence and development of PBS indicative of nicotine dependence in never smokers and novice smokers and the underlying neurobiological mechanisms as a function of the level of ETS exposure. Therefore, we…
The primary objective of this project is to map differences in joint loading between athletes receiving visual feedback and those who will not receive visual feedback in both retention and transfer to field-specific situations. From there. we will…
The primary objective of this study is to measure mitochondrial capacity using NIRS in young and older healthy males in three different muscles (vastus lateralis, gastrocnemius and the tibialis anterior) to give insights on how age-related changes…
Our aim is to improve patient and doctor satisfaction and quality of the discussion about potential treatment restrictions by introducing a digital information and conversation aid for patients and training for doctors. Moreover, we aim to provide…
The purpose of the study is to investigate how quickly and to what extent Orgaran® is absorbed and eliminated from the body (this is called pharmacokinetics) in comparison to Clexane® and in relation to the results of the earlier studies performed…
To contribute to building a sound scientific basis for the regulatory EU institution to set-up occupational exposure limits and related biological limit values, as well as reference values for the general population and to study the impact of the…
The purpose of this study is to investigate how well 2 combinations of devices for continuous monitoring of vital signs (in this case pulse rate, breathing frequency, peripheral oxygen saturation [SpO2], and skin temperature) work when used in…
The research should both personal and societal interests. Through the GPSplus to relieve the caregiver will use envisaged by the patient is not continuous in the holes to worry if it goes outside. In addition, there would be a decrease in problem…
To investigate the effects of oxygen therapy within the first hour on the occurence of oxidative stress biomarkers at different levels of oxygenation (hypoxia, normoxia and hyperoxia).
The primary objectives are to investigate attentional interference by somatosensory itch and pain stimuli in healthy subjects, both on a behavioural (SAT) level and a neurophysiological level (EEG alpha-desynchronization).Secondary objectives…
In the proposed project we evaluate the potential benefits and feasibility of including (a) a decision support system, *Clinical Rules Engine* (CRE) and (b) patient preferences, using the *Outcome Prioritization Tool* (OPT) in a comprehensive…
The primary objective is to demonstrate the non-inferiority of rivaroxaban 10 mg versus enoxaparin 4000 IU relevant to the occurrence of major VTEs up until the end of the treatment (for example, cast or splint removal). The power of the study…
Primary Objective:Efficacy:· Evaluate the efficacy of subcutaneous (sc) azacitidine in combination with durvalumab as compared with subcutaneous azacitidine alone in the defined study population.Secondary Objectives:Safety:· Assess the safety and…
To investigate whether there is a difference in gastric volume over time after ingestion of cow milk between lactose tolerant, habitual milk consumers reporting no GI symptoms and non-habitual milk consumers reporting GI symptoms after milk…
to assess the endodontic and restorative survival of teeth after root canal treatment and the endodontic and restorative success of the root canal treatment performed at the Special Dental Care Center of the Martini Hospital.
Primary Objective:- Long-term safetySecondary Objective:- Survival- Clinical efficacy of AUTO CAR T cell therapy in patients enrolled prior to disease progression- Chimeric antigen receptor (CAR) transgene persistence- Replication competent…