145 results
1. Is the concentration of brain specific proteins in CSF higher in newborn who are treated after high threshold as compared to newborns who are treated after low threshold?2. Is there any relationship between the concentration of brain specific…
The aim of this study is to evaluate the role of MLPA in a routine clinical setting for detecting firstly, DS and secondly, the most common chromosomal aberrations compared to TKT (gold standard) in prenatal diagnosis.Is diagnostic accuracy of the…
The research question of this study is whether BIND is reduced using B:A ratios in addition to TSB versus TSB only as indicators for treatment of hyperbilirubinemia in preterm infants.
The primary objective of this study is: * to provide baseline normative data of the fetal face. The secondary objectives of the study are: * to compare two-dimensional ultrasound with three-dimensional ultrasound in evaluating the fetal face. * to…
The primary objective is to compare metformin versus no intervention for incidence of GDM in women with a high risk for GDM. The main secondary objective is pregnancy outcome with Metformin, neonatal outcomes and neonatal complications.
This study will investigate whether bone marrow-derived allogeneic MSCs, as administered by the nasal route, can induce the formation of neuronal tissue and restore brain function in neonates who suffered from perinatal arterial ischemic stroke (…
1- to describe the presence and severity of hemiplegic CP on the basis of neonatal MRI findings and correlate the involvement of different structures (basal ganglia, posterior limb of the internal capsule and hemisphere) with the size of the lesion2…
The hypothesis is that SMBG underestimates the number of hyperglycaemic episodes in women with gestational diabetes mellitus. The aim of this study is to evaluate if CGMS detects hyperglycaemia when the standard SMBG day curve is normal.
To evaluate detection thresholds, functioning of the HPA-axis and risk of chronic pain in children of 5-years of age who experienced pain and received morphine in neonatal period in compare with children of 5-years of age who experienced pain…
To describe serial changes in diastolic and systolic myocardial performance by comprehensive echocardiographic assessment in neonates prior to, during, and after ECMO treatment and relate this to the course of PPHN.
This study aims to validate NI-fECG monitoring as an accurate and reliable monitoring technique for FHR, MHR and UA surveillance during labour. The aim of this validation is to work towards clinical implementation of NI-fECG monitoring.
To investigate the association between preterm brain injury, impaired brain development and neurodevelopmental outcomes 9-10 years after VPT birth
ICG allows continuous, non-invasive monitoring of the CO. ICG is a method that detects changes in thoracic electrical bioimpedance between simple skin electrodes, together with a conventional ECG. To estimate CO, it uses complex algorithms based on…
Primary objective: To determine the association between serum adiponectin and the risk of developing gestational diabetes. Secondary objective: To determine the association between serum leptin in pregnancy and the risk of developing gestational…
We aim to examine the differences in response of hemodynamic and ventilatory parameters between women in their first trimester of pregnancy and non-pregnant women during a CPET.
The main objectives are: to determine whether early and serial EEG brain monitoring, is a bedside biomarker for later structural brain maturation and microstructural brain development and to examine whether serially EEG-measured brain function is…
This pilot study aims to explore the possible technical and practical problems that may be encountered when intrapartum NI-fECG monitoring is performed (PF2 study). The results of this pilot study will be the basis for a larger validation study…
To assess the efficacy of the novel kit for the detection of PAMG-1 in the cervico-vaginal secretions of pregnant women with clinically intact membranes presenting with signs and symptoms of PTL in predicting time-to-delivery.
Do neonatal critically ill children aged 9-16 years have problems with visuomotor integration? If yes, which aspects of the visuomotor integration are affected and require a possible intervention?
(1) Longitudinally describe the language and speech development in preterm children at 9 years of age. (2) Investigate whether these outcomes are related to a divergent development of neurological (language) system and (3) whether these language and…