32 results
In this study we will assess the optimal analytical conditions for routine laboratory GDM screening in the Netherlands, possible discrepancies in clinical outcome due to (pre)analytical variation and the applicability of POCT testing in GDM…
The development of a disease specific questionnaire to measure the quality of life in children with BPD at age 4-8, that can be answered by the parents.
The main objective of this study is to analyze women's decision making processes regarding an unintended pregnancy in order to improve the counseling (in abortion and reproductive health clinics) for these women.
To evaluate the bowel function, quality of life and nutritional status in adolescents/adults who experienced an episode of NEC at neonatal age.
To evaluate and obtain insight into psychological, social and moral factors in thoughts and attitudes of pregnant women and their partners carrying a fetus with an isolated CL ± P in order to improve counseling.
The primary objective of this pilot study is to assess the prevalence of visual field defects in formerly eclamptic women. The secondary objective is to compare the vision-related quality of life between formerly eclamptic and normotensive parous…
To assess in women with a request for pain relief during labour the cost-effectiveness of remifentanil patient controlled analgesia (RPCA) as first choice compared to EA.
The primary objective of this study is to determine the prevalence of white matter lesions and subjective/objective neurocognitive functioning in women several years after pregnancy compared to nulliparous women The secondary objective is to…
1. To determine the rate of splanchnic utilization of glutamine, proposed to be conditionally essential for premature infants.2. To quantify the rate of splanchnic oxidation of dietary glutamine, which is supposed to be one of the major fuel…
To quantify splanchnic and whole body aspartate metabolism in premature neonates.
We intend to employ an ex vivo model of human implantation to study the factors involved in successful implantation. By linking parameters of successful implantation with embryo quality markers, we aim to improve embryo selection and IVF outcomes.…
1- To determine the physiological concentrations of ADAM12 and PP13, longitudinal, in the early first trimester in normal pregnancies. 2- To analyse the stability of these proteins, the effect of transport and higher temperatures.3- To compare the…
A study will be conducted to investigate whether screening for PE and growth restriction not associated with PE in the Dutch setting is feasible.
Epidural analgesia (EA) is an effective method to reduce labour pain. At present, it is unknown whether use of EA increases labour complications, and what the costs of EA are. In this proposal, we assess the impact of a proactive policy of offering…
To increase our understanding of the developmental significance of chromosomal mosaicism in preimplantation embryos by investigating their implantation potential and the fate of abnormal cells after an in vitro implantation procedure.
In this study we aim to compare the effect of two different ovarian stimulation protocols on embryo quality in a group of women of 39 years or younger, in a prospectively randomized controlled trial. PGS will be performed to assess chromosomal…
Aims of this study is to explore factors that are related to (sub)optimal mother-child bonding in mothers with mental health disorders.
In this study the primary objective is to investigate whether activation of TRPV1, TRPA1 and TRPM3 by selective channel agonists induces vasodilation in human dermal arteries. If the primary objective is achieved, the secondary objective is to…
To determine the accuracy of the *NeoBeat* device against gold standard measurements obtained by an ECG monitor with disposable (gel) electrodes and against pulse measured preductally as derived by pulse-oximeter.
Primary objective:Are postpartum PTSD symptoms an independent predictor for impaired mother-child bonding, or does insecure attachment in mothers, also play a role in this?