33 results
a. To investigate the phenotype and function of immunological cells present in endometrial and peripheral blood of women with a history of recurrent miscarriages and women without any known pregnancy complications.b. To investigate the association…
Primary Objectives: - To evaluate the safety in mother and neonate/infant of nipocalimab administered to pregnant women at high risk for EOS-HDFN. - To evaluate the efficacy of nipocalimab as measured by proportion of patients with live birth at or…
Primary objective: To identify those groups of pregnant patients, planned to undergo cesarean delivery, who are at risk to develop severe hypotension (defined as a decrease of at least15% from the baseline tension) based on their preoperative volume…
To evaluate the effectiveness and cost-effectiveness of intensive GDM treatment as compared to routine maternity care in pregnant women with a discordant OGTT result between the new (2013) WHO criteria as compared to the old (1999) WHO criteria for…
Aims of the study:1. To evaluate the effect of a guided self-help resilience training for pregnant women with depressive symptomatology on:a) primary outcomes: maternal depressive symptoms and resilience; andb) secondary outcomes including maternal…
The main objective of the Brabant Study (BS) is to investigate possible different trajectories of thyroid function during pregnancy taking hCG hormone into account. Moreover, we aim to investigate whether pregnancy complications (e.g. pre-eclampsia…
To compare the effect of umbilical cord clamping after cardiopulmonary stabilisation (Physiological Based Cord Clamping; PBCC) to standard care (Time Based Cord Clamping; TBCC) on intact survival and health care costs in preterm infants.
The aim of this study is to evaluate the diagnostic value of sCD14-ST in the diagnosis of neonatal sepsis. The secondary aim is to evaluate whether serial measurement of sCD14-ST after suspected sepsis onset is of additive predictive value for the…
The main aim of this study is to examine associations between maternal cardiovascular adaptation to pregnancy and utero(placental) vascular development in women who do and do not develop PPC. Therefore, we specified the following objectives:1. To…
Does, in late preterm fetuses identified as small-for-gestational-age (SGA), timing of delivery based on abnormal umbilicocerebral ratio (UCR) improve neurodevelopmental outcome?
The effect of continuous care during childbirth care compared with current standard care, in which continuous guidance has not yet been achieved.
The overall aim of this study is to assess WML and associated existing and novel SVD imaging markers to dissect the pathophysiological mechanisms underlying WML in young to middle aged women at risk for future cardiovascular disease. We aim to…
We will assess the (cost-)effectiveness of implementing two interventions in the birth centre setting:1. TcB measurement as a non-invasive screening tool to identify jaundice.2. Application of phototherapy in the birth centre.We hypothesise that…
The influence of mobilisation of the sacroiliacal joint and an stabilizing or relaxation exercise program on pain, the function of the pelvic floor, the m. Transversus Abdominus and functional state in patients with pelvic girdle pain.
Primary ObjectiveIn order to assess the effects of anti TNFα on the development of adaptive and innate immunity, children exposed to anti TNFα (with or without other immunosuppressive drugs) will be compared to children exposed to immunosuppressive…
The objective of our study is to investigate whether application of the PreRisk calculator, based on the sFlt1/PlGF ratio,protein-to-creatinine ratio and gestational age, in patients with (suspected) PE can reduce the number and duration of…
To investigate the effect of increasing gestation on fetal myocardial deformation values.To explore fetal heart rate variability and fetal ECG waveform parameters in both healthy and growth-restricted fetuses, measured with non-invasive fetal…
The primary aim of this study is to investigate the safety and feasibility of ultra-high field magnetic resonance imaging (MRI) of the brain in neonates and to optimize scan protocols.
The goal of this study is to assess the long-term impact on child*s cognitive- en neurodevelopment, growth and health in children born from mothers with preterm prelabor rupture of membranes (PPROM) between 34 and 37 weeks* gestation.
The FAST Therapy Trial is a prospective trial of patients with a new diagnosis of fetal SVA aimed to compare the impact of different perinatal treatment strategies from the time of SVA diagnosis to birth or death1) The primary outcome will be the…