31 results
The primary objective of the study is to examine muscle atrophy in fetuses with single or bilateral IPEV, in comparison to a normal population by measuring the circumference of the upper and lower legs by ultrasound examination. The length of the…
In this project we hypothesize that recurrent pregnancy miscarriages is an issue stemming from both the female as the male. The overall aim is to elucidate paternal factors associated with RPL (A) and to assess the predictive value of these factors…
The main objective of our research is to study the effectiveness of the SAFER pregnancy intervention in reducing risk behaviour (i.e. smoking and alcohol use) in pregnant women and women with the wish to conceive. The secondary objectives focus on…
Primary Objective: analyse the effect of maternal BMI on levels of macrophage cell and monocyte subsets in decidual tissue and maternal blood. Secondary Objective: analyse differences in the effect of maternal blood stimulation with conditioned…
The main goal of this study is to analyse NK cell phenotype in women with unexplained recurrent miscarriage in relation to their physical health.
The main objective is to pinpoint the biological pathways that set long-term risk of CVD and NDI when epigenetically disturbed during fetal development by (1) establishing a longitudinal cohort of MC twins, (2) defining epigenetic alterations…
The primary objective of this study is to assess the effectiveness of myo-inositol supplementation to prevent pregnancy complications in women with PCOS. Secondary objectives are to evaluate the impact of supplementation on maternal (mental) and…
Zie protocol, hoofdstuk 3 (Objectives)
To assess embryonic, foetal and placental growth trajectories by serial assessments of sizes and volumes and foetal morphology during the first, second and third trimester of pregnancy with the aim to examine whether BS influences embryonic growth…
To compare the effect of a HCPAP with LCPAP on oxygenation in the first 5 minutes during stabilization in preterm infants at birth.
To assess if prompt start of labour (<16 hours) of a fetus with RFM, based on CPR <1.1 in term pregnancy will improve the neonatal outcome (including perinatal mortality and long-term (neurodevelopmental) outcome) and maternal outcome…
Primary Objective: - to establish if a gut microbiome perturbation affects APS disease phenotype.Secondary Objective(s): - to identify biomarkers that are responsive gut microbiome perturbation.- to establish if gut microbiome perturbation affects…
This study will evaluate if neonatal effects as described in previous studies are seen in delayed umbilical cord clamping in caesarean sections. Moreover, we will review the maternal effects compared to conventional cord milking in caesarean…
Primary Objective: To evaluate whether PBCC results in a reduced incidence of pulmonary hypertension in infants with CDH 24hrs after birth.Secondary Objectives: To measure and monitor physiological parameters during transition to provide information…
This study is conducted to discover if bacterial vaginosis is related to the pregnancy rate in couples undergoing assisted reproduction.
To determine the workability of the non-invasive abdominal electrode patch for implementation in clinical practice.
Primary objective: to research if Paracetamol reduces Remifentanil use when added to Remifentanil/PCA pain management during labour. Patients: Women in labour, using Remifantanil as pain management Intervention: Paracetamol intravenous (1 gram,…
Primary: To evaluate the tolerability and safety of the treatment with rhC1INH (conestat alfa) on top of Standard Care, for patients with pre-eclampsia.Secondary: To evaluate the efficacy of treatment with rhC1INH (conestat alfa) on top of Standard…
The primary objective is feasibility of performing BOLD MRI of the placenta in our centre.
To evaluate the long-term neurodevelopmental outcome in two groups of children with FNAIT. First, children with unanticipated disease *index cases* that were born without maternal IVIg administration during pregnancy. Second, children with…