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Mifepristone and misoprostol versus misoprostol alone for uterine evacuation after early pregnancy failure: a pilot study

Th**is study will compare sequential mifepristone and misoprostol (*M&M*) treatment versus misoprostol treatment alone, which is currently the standard medical treatment in the Netherlands.

What should be done in women with an incomplete evacuation of the uterus after treatment with misoprostol for miscarriage? An analysis of costs and effects.

To assess costs and effects of curettage versus expectant management in women with incomplete evacuation of a miscarriage, as diagnosed with sonography, after misoprostol.

Parental Attitude towards CL ± P during pregnancy;To evaluate and obtain insight into psychological, social and moral factors in order to improve counseling.

To evaluate and obtain insight into psychological, social and moral factors in thoughts and attitudes of pregnant women and their partners carrying a fetus with an isolated CL ± P in order to improve counseling.

The developmental and implantation potential of aneuploid and mosaic human embryos, as assessed in an in vitro model

To increase our understanding of the developmental significance of chromosomal mosaicism in preimplantation embryos by investigating their implantation potential and the fate of abnormal cells after an in vitro implantation procedure.

A study of the effects of a novel ovarian stimulation regimen on embryo aneuploidy rates in IVF, and the impact of aneuploidy on implantation, as assessed in an in vitro model.

In this study we aim to compare the effect of two different ovarian stimulation protocols on embryo quality in a group of women of 39 years or younger, in a prospectively randomized controlled trial. PGS will be performed to assess chromosomal…

Reasons for induced abortion

The main objective of this study is to analyze women's decision making processes regarding an unintended pregnancy in order to improve the counseling (in abortion and reproductive health clinics) for these women.

Immunological determinants of human embryo implantation: an ex vivo model

We intend to employ an ex vivo model of human implantation to study the factors involved in successful implantation. By linking parameters of successful implantation with embryo quality markers, we aim to improve embryo selection and IVF outcomes.…

A Multicenter, Open-Label Study to Evaluate the Safety, Efficacy, Pharmacokinetics and
Pharmacodynamics of M281 Administered to Pregnant Women at High Risk for Early Onset Severe
Hemolytic Disease of the Fetus and Newborn (HDFN)

Primary Objectives: - To evaluate the safety in mother and neonate/infant of nipocalimab administered to pregnant women at high risk for EOS-HDFN. - To evaluate the efficacy of nipocalimab as measured by proportion of patients with live birth at or…

Mifepristone and misoprostol versus misoprostol alone for uterine evacuation after early pregnancy failure: a randomized double blind placebo-controlled comparison (Triple M trial)

This study will compare sequential mifepristone and misoprostol treatment versus misoprostol treatment alone, which is currently the standard medical treatment in the Netherlands.