30 results
The primary objective of this study is to determine the ability to diagnose (in a clinical validation study) the health of the early foetus by using the non-invasive nanoCAGE RNA-sequencing test using circulating cell-free RNA isolated from first…
The main objective of this study is to analyse the effect of fetal sex on levels of T and macrophage cell subsets in decidual tissue. Secondary objectives will be to analyse differences in the effect of maternal blood stimulation by fetal leukocytes…
To determine the vaginal microbiota composition during preeclampsia
The primary objective of this study is to generate reference values for NFMS parameters as well as for 2D-STE parameters during the second trimester, 16 until 28 weeks gestational age. The secondary objective is to investigate the diagnostic…
The overall aim of this study is to assess WML and associated existing and novel SVD imaging markers to dissect the pathophysiological mechanisms underlying WML in young to middle aged women at risk for future cardiovascular disease. We aim to…
The aim of the DONOR study is to define if OD pregnancies, specifically those with immunogenetic differences between mother and child, are associated with abnormal placentation and vasculogenesis, resulting in distinct maternal immunomodulation and…
- to analyze the changes in the gut microbiome of IBD patients during pregnancy and try to find an association with disease activity - to analyze whether changes in the gut microbiome remain after post partum period of 3 months-to analyze gut…
a) To evaluate whether PAPP-A2 and inhibin A could be used as biomarkers for preeclampsia and preeclampsia-related outcome in twin pregnancies. To achieve this objective, we will first assess:- Whether PAPP-A2 and inhibin A levels are increased in…
To identify differences in immune cell repertoire between pregnant women with critical COVID-19, mild COVID-19 and healthy controls.
We hypothezise that hypertension in pregnancy, spontaneous preterm birth and cardiovascular disease in later life share pathophysiological features of endothelial dysfunction. We will investigate this on two levels including local on tissue level…