69 results
The aim of this study is to determine whether children between 5-17 years born to women with an autoimmune disorder and prednisone use during pregnancy have chronically elevated cortisol levels compared to children born to women with an autoimmune…
With this research project we will investigate the relationship between SSRI concentration in the (pre)term neonate and clinical short and long term effects on the neonate after exposure to SSRI*s during pregnancy and lactation. Furthermore, the…
Cross-sectional study: To detect the normal range of amplitudes and segment intervals of the fECG. Case-cohort study: To compare the fECG between healthy fetuses and fetuses with various forms of severe CHD. To determine the diagnostic value of fECG…
Primary objective: to determine the incidence and location of thrombi in the umbilical venous catheter route during and after umbilical catheterization and in the same route in infants without umbilical catheters. Secondary objectives:A. to…
To determine the feasibility of rs-fMRI in neonates undergoing a planned diagnostic MRI session following perinatal asphyxia. To assess intra-session reproducibility (test-retest reliability) of the rs-fMRI technique in neonates with asphyxia.
To determine whether administration of exogenous surfactant using a minimally-invasive technique improves outcome in preterm infants 25-28 weeks gestation treated with continuous positive airway pressure (CPAP).
To obtain reference values of rsO2 of cerebral and muscle tissue measured by NIRO 200 NX for (relatively) healthy near term and term neonates.
To determine whether increased calcium and phosphate intake (2005 group) resulted in improved Bone Mineral Content (BMC) and Bone Mineral Density (BMD) compared to the group with less calcium and phosphate intake (2004 group) at the age of 8-10…
It is hypothesized that advanced hemodynamic monitoring will result in earlier detection of circulatory failure in critically ill newborn infants compared to clinical assessment of shock, which is the actual standard diagnostic tool in daily…
First objective: To assess late neonatal neurological outcome in infants with duct dependent CHD and to gain more insight into the timing of brain damage. We will determine whether the quality of GMs at an age of seven days and three months is…
The aim of the study is to gain more insight in the course of intestinal oxygenation, urinary I-FABP concentration, and plasma Citrulline levels (as markers for intestinal damage and recovery) after NEC in relation to time to full enteral feeding…
The aim of the trial is to obtain data on the optimal dose, feasibility and pharmacokinetics of bumetanide when given as an add-on treatment for seizures in full term babies with hypoxic ischemic encephalopathy (HIE). Bumetanide will be given in a…
To establish normal ranges for the lateral ventricles in neonates with a gestational age ranging from 25 to 42 weeks.
In this multicenter trial we compare resuscitation of preterm neonates with either 5 cm H2O PEEP or 8 cmH2O PEEP. We think resuscitation with 8 cmH2O PEEP results in a better outcome compared to resuscitation with 5 cmH2O PEEP.
Evaluation of the effects of intravenous lipid and extra amino acid supplementation from birth onwards to very low birth weight infants on amino acid turnover and protein accretion. As secondary objectives the safety, energy expenditure and short-…
To evaluate the course of concentrations of oxidative stress parameters and neuro-biomarkers in cord blood, serum and urine of full-term asphyxiated neonates. Furthermore, to investigate whether these concentrations are correlated to hypoxic…
The objective is to study the effectiveness of the Triple P program compared to a control group, for parents and their NICU-graduates with emotional and/or behavioral problems. Effectivenes concerns children's problems, parents' parenting…
A:To get insight whether respiratory support in the neonatal population, as artificially ventilation and Nasal Continously Positive Airway Pressure, will give an increased stress or pain respons which only can be detected by a 24 hours SCA…
The ultimate goal of this research is the clinical implementation of a non-invasive test for prenatal fetal genotyping, including fetal sex determination, using cff DNA in maternal plasma, to replace the current standard practice of invasive tests,…
To answer the following questionsDo RA-specific autoantibodies cross the placenta, and can they be found in fetal cord blood in the offspring of mothers suffering from RA?Do RA-specific autoantibodies in fetal cord blood display different…