38 results
The quality and quantity of the innate immune response to bacteria should be tightly regulated leading to resolution of infection while minimizing damage to host tissue. We hypothesize that this regulation depends on gestational age at delivery and…
The objective of the study is to identify biomarkers that associate to brain (physiological) status or mental (functional) health status and their interaction. More specific, our first aim is to determine the association between neuroinflammatory…
To explore cardiovascular remodelling with subsequent altered cardiac function (assessed as strain rate) in extremely premature neonates (born <30 weeks and/or birth weight < 1000 gram) with FGR.
The primary objective is to study the association between maternal TL and the risk of SB in offspring. The secondary objectives are to investigate the relation between maternal TL and obstetrical (pregnancy course and outcome), environmental risk…
The primary objectives of the NO GBS study part 1 are to: - determine the clinical characteristics and outcome, and the prevalence of risk factors used by Dutch guidelines for risk assessment in GBS and E. coli meningitis and sepsis cases aged 0-3…
In this observational cohort study we will determine the prevalence and genetic profile of colonizing GBS isolates in pregnant women in the Netherlands. We will collect serum from pregnant women and their newborns to determine specific IgG…
In 2004, a multidisciplinary team of clinicians and researchers in the UZ Leuven hospital started to collaborate on the rare problem of cancer during pregnancy. The collaboration between gynaecologists, pediatricians, hematologists, farmacologists,…
The objectives of the study are to:A. Determine the effects of music therapy during skin-breaking procedures on the pain response in infants admitted to a NICU or HC ward.B. Determine the effects of music therapy during skin-breaking procedures on…
The aim of this study is to characterize the composition of amniotic fluid, collected during preterm delivery, of extremely preterm infants (24-28 weeks), using novel molecular techniques. These approaches include microbial (e.g. IS-pro analysis)…
The objective of the NEK-study is the clinical relevance of increased nuchal translucency in fetuses with a CRL <45mm and NT measurement of >=2.5mm. Expectant parents can receive better counselling for their ongoing pregnancy if the…
To obtain a fundamental understanding if and which chemotherapeutic agents used for treating cancer during pregnancy are associated with offspring (epi)genetic changes, potentially causing FGR and childhood/adult diseases later in life.
Our main objective is to explore the relationship between nutritional intake, growth, body composition and brain development. Hereby we want to improve our knowledge about how to feed the preterm infant in a way that contributes to a better…
1.To explore the intrauterine cerebral development by ultrasound in healthy fetuses to compare to the findings in fetuses with severe CHD. We want to do this by establishing benchmark values in healthy control fetuses, to compare these with our…
To study cognitive and behavioral outcome and resting-state dynamics in children with a history of perinatal asphyxia before and after the introduction of hyothermia and to compare these data with a group of controls.
To determine the feasibility of measuring SpO2 and HR by applying a pulse oximetry probe to the umbilical cord at birth in term neonates undergoing PBCC.
The primary objective of this study is to investigate the effects of stress exposure on the epigenetic profile of preterm infants. Secondary objectives include to determine (a) the relation between stress exposure and early childhood outcomes (…
In this research study we observe the effect of breathing on placenta- to infant transfusion, by measuring bloodflow in the umbilical vein, vena cava inferior, ductus venosus and hepathic vein, to get a better understanding of the underlying…
First, to compare MLP children with FT and with EP peers regarding intelligence at age 14 to 15 years. Second, to compare MLP children with FT and with EP peers regarding health, health-related behaviors, growth measures, blood pressure, pubertal…