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Safeguarding the brain of our smallest children ;* an investigator-initiated randomised, blinded, multinational, phase II
feasibility clinical trial on near-infrared spectroscopy monitoring
combined with defined treatment guidelines versus
standard monitoring and treatment as usual in premature infants

The primary objective of the SafeBoosC trial is to examine if it is possible to stabilise the cerebral oxygenation of extremely preterm infants (gestational age < 28 wks) during the first 72 hours of life through the application of cerebral…

EARLY DETECTION OF SHOCK IN CRITICALLY ILL NEWBORN INFANTS.
The impact of advanced hemodynamic monitoring

It is hypothesized that advanced hemodynamic monitoring will result in earlier detection of circulatory failure in critically ill newborn infants compared to clinical assessment of shock, which is the actual standard diagnostic tool in daily…

Non-invasive prenatal diagnosis using cell-free fetal DNA in maternal plasma.

The ultimate goal of this research is the clinical implementation of a non-invasive test for prenatal fetal genotyping, including fetal sex determination, using cff DNA in maternal plasma, to replace the current standard practice of invasive tests,…

Immune development in early life

1. To describe the development of the nature of the immune system in early life in a profile of cytokines, chemokines and adipokines. 2. To evaluate less invasive methods like the use of saliva or less demanding methods like the use of dried bloods…

Implementation of a cost effective strategy to prevent neonatal infection by group B-hemolytic streptococcus

To find the most cost effective GBS prevention strategy to reduce neonatal morbidity and mortality by GBS for the Netherlands.

Healthy Pregnancy 4 All - Preconception Care

The objective of the study is to contibute to the improvement of perinatal outcomes by means of optimisation of preconception care via child wish consulting hours at general practioner and midwife practices.