149 results
Is it feasible to measure mean systemic filling pressure (Pmsf) and ΔetCO2 secondary to an incubator tilt maneuver in newborn infants?
To compare neonatal mortality and short-term (advanced MRI indices of structural brain injury at 40 weeks* GA) and long-term neurodevelopmental outcomes (Bayley scales of infant development III [BSID-III] at 24 months) between two groups of very…
1) To test the feasibility of vaccinating pregnant women against B. pertussis in preventing B. pertussis infection in newborn babies.2) To test the safety of vaccinating pregnant women against B. pertussis in preventing B. pertussis infection in…
In this study we want to determine the most adequate parameters (clinical, echocardiographic, Near Infrared Spectroscopy (NIRS) and B-type Natriuretic Peptide (BNP)) to diagnose a hemodynamic significant PDA. A second objective is to gather normal…
The main question in the study isHow do moderately preterm infants and their parents differ from term, as well as extreme preterm infants in (a) development and self regulation skills of the infants, (b) interaction patterns and relationship between…
Objective #1: Implement clinical platform. We see the need to implement a clinical platform for two purposes. First, we want to design a biomarker profile of perinatal brain damage in human newborns (see above). Thus, we have established a…
Investigate the effect of acidic and neutral oligosaccharides supplemented enteral nutrition on infectious morbidity, feeding tolerance and short-term outcome in VLBW infants. Furthermore, an attempt is made to elucidate the role of acidic and…
In this study, we will investigate the use of optical spectroscopy in determining neonatal bilirubin and hemoglobin blood levels. The outcome and accuracy of the optical spectroscopy measurements will be compared to the outcome of laboratory blood…
The aim of this study is to describe and learn more about parenting attitudes, laxness and overreactivity, the ability to set limits and parenting stress in fathers and mothers of children born preterm at the age of 5 to 7. Hypotheses will be tested…
1. To prevent multiple pregnancies and the concomittant neonatal mortality and morbidity while retaining acceptable delivery rates in couples with unexplained subfertility or mild male subfertility and poor fertility prospects. 2. To assess the…
To assess the effects of Cognitive Behavioral Therapy (CBT) in pregnant women with symptoms of anxiety or depression on the child*s behavioral/emotional problems. In addition, we aim to study its effects on the child*s development, maternal mental…
This project aims to develop an evidence based effective and "safe" dosing regimen for commonly used life saving medicationsused in the treatment of asphyxiated, critically ill newborns, undergoing therapeutic hypothermia.To this aim the…
To evaluate the predictive value of microcirculatory perfusion for the incidence of Extracorporeal Membrane Oxygenation (ECMO) dependency and consequently survival. To evaluate the effects of vasopressor drugs and iNO on microcirculatory perfusion.
The final aim of the study is the implementation of a test for the detection of fetal Down syndrome via noninvasive procedures, with the same characteristics as the tests that are currently being used (sensitivity and specificity). This test can…
Study (population) pharmacokinetics of midazolam, morphine, phenobarbital and lidocaïne during therapeutic hypothermia for adequate dose adjustments.
To establish microcirculatory profiles using non-invasive diagnostic imaging in NEC.
The main objective of the study is to provide insight in the developmental problems of very premature and/or VLBW children compared to their term born peers, and to investigate the possible beneficial longitudinal effects of the GEEF intervention on…
The objective of this study is to examine the consequences of the use of an SSRI in pregnancy for motor and cognitive development of the child, in the short and long term.
Our preliminary data shows that the prescription rate of antibiotics for suspected EOS versus blood culture proven EOS was high. We aim to develop a new diagnostic model to reduce unnecessary antibiotic treatment which can be tested in the near…
Primary Objective: To investigate whether spatially resolved NIRS can differentiate between a patent or closed ductus arteriosus.