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The Home Sweet Home study: An observational, longitudinal study on the home environment of people with chronic obstructive pulmonary disease (COPD).

Primary objectives:1.1 To investigate the differences between patients* and resident loved ones' perceptions of patients* health status and problematic ADLs.1.2 To study prospectively the effects of an acute COPD exacerbation on resident loved…

Point-of-Care C-reactive protein to assist in primary care management of children with lower respiratory tract infection

Analyse costs and effects of point of care (POC) C-reactive protein (CRP) measurement in children with non-severe lower respiratory tract infection (LRTI) in primary care.

GOLD D in primary care: a group whose clinical outcomes can easily be improved

The aim of the current study is evaluation of the Certe A/C service system. This is achieved via 2 workpackages:Workpackage 1 constitutes of describing patient characteristics (age, gender, current medication, smoking status and comorbidities) of…

The validity of performance tests, the 4 meter gait speed and the 5 repetitions sit to stand test, in patients suffering PF in daily clinical practice

Objective: The aim of this study is to assess the validity of the 4MGS and 5STS to determine the functional exercise performance of PF patients.

eVita COPD; Patient Centered Care through eHealth Solutions

The main aim is to investigate clinical effects of different implementation methods of online supported self-management for COPD patients in primary care. Secondary objectives include effects on well-being, health care use and actual use of the…

New Therapies for bone and cartilage defects using bone marrow

The aim of the basic research in the laboratory is to develop new treatments to repair large bone defects, repair cartilage defects or inhibit the progression of osteoarthritis (cartilage degeneration). We focus on the following questions:1.How can…

HOMERUN
Initiation of HOme MEchanical ventilation at home in a selective group of patients with chronic hypercapnic Respiratory failUre in the Netherlands

Patients with chronic respiratory failure currently start their ventilatory support in hospital as stated in national guideline. However, as these patients are severely disabled, a stay at the hospital for several days is experienced by many as very…

myAirCoach * The use of home-monitoring and mHealth systems to predict asthma control and the occurrence of asthma exacerbations

Therefore, the aim of the myAirCoach project is to develop and evaluate technologies that assist patients with asthma. To this purpose we developed a one year observational quantification campaign in which we will identify potentially relevant self-…

COPD coaching intervention Friesland

This study aims to investigate the process and outcome of the implementation of a coaching intervention in COPD care in the Friesland province.

Bronchiolitis obliterans syndrome and other allo-reactive lung syndromes
after allogeinic hematopoietic stem cell transplantation
Is early prediction of bronchiolitis obliterans possible by using biomarkers possible?

In this study we would like to find new biomarkers in BOS after haematopoietic stem cell transplantation (HSCT), that may lead to earlier identification of BOS than a lung function decline.

A decision model for the management of acute exacerbation chronic obstructive pulmonary disease in the emergency department: flowchart for treatment allocation.

The primary objective is to validate a previously established prognostic instrument in the form of an algorithm (flowchart) in patients that present with AECOPD to the department of emergency medicine for classifying for out- or inpatient treatment…

Pilot study: Respiratory microbiome analysis by the IS-pro technology

Different sampling methods have been used for respiratory microbiome analyses, including both invasive as well as non-invasive techniques. We would like to investigate if the results of the bronchoscopy are comparable with results from the nose swab…

CRP-POCT in suspected airway infected patients in the long-term care facility

The main objective is to investigate the additional value of CRP-POCT (C-reactive protein point-of-care-test) testing in patients suspected of airway infections in long-term care facilities.

The use of a point-of-care thoracic ultrasound protocol for hospital medical emergency teams

Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.

Systemic sclerosis: CT-derived evaluation of interstitial lung disease and pulmonary vasculopathy for assessment of progression of disease.
Research protocol for extended volume HRCT-thorax in patients with systemic sclerosis participating in a 2 *day multidisciplinary team care program of the department of Rheumatology and Pulmonology

zie nederlandse samenvatting

An exploratory study to assess the RSV titer in healthy volunteers as guidance for the main study

To determine pre-existing virus neutralization titer levels against RSV in a general healthy population (immunogenicity is a secondary study objective (proof-of concept) in the main phase I study).

Client IMplementation PatientCoach (CIMP)

The purpose of the study is to evaluate the usability of PatientCoach by patients with asthma and/ or COPD,hypertension and/or Diabetes Mellitus.

A 3-month Multicenter randomized trial to evaluate the efficacy of a Physical Activity Promotion Program on the experience of physical activity in patients with COPD (Mr PAPP)

The purpose of this study is to test the impact of a physical activity promotion program which is a personalized, semi-automated, coaching program utilizing an smartphone on which an app is installed and coaching by the investigator. The automated…

Co-infections in bronchiolitis: incidence, clinical symptoms and influence of cohortisolation

The purpose of this study was to determine the incidence and severity of co-infection in children hospitalised for bronchiolitis, when cohorting of RSV-infected patients is omitted. . Furthermore we want to elucidate general epidemiological data on…

Correlates of the COPD Assessment Test (CAT) after stratification for GOLD stages and its response to pulmonary rehabilitation in patients with moderate to very severe COPD.

The main objective of this study is the clinical, physiological and psychosocial determinants of CAT in a broad sample of patients with moderate to very severe COPD and the impact of co-morbidities on the HRQL assessed with CAT. Secondary objectives…