84 results
Objective: The aim of this study is to assess the validity of the 4MGS and 5STS to determine the functional exercise performance of PF patients.
The aim of the basic research in the laboratory is to develop new treatments to repair large bone defects, repair cartilage defects or inhibit the progression of osteoarthritis (cartilage degeneration). We focus on the following questions:1.How can…
In this study we would like to find new biomarkers in BOS after haematopoietic stem cell transplantation (HSCT), that may lead to earlier identification of BOS than a lung function decline.
Different sampling methods have been used for respiratory microbiome analyses, including both invasive as well as non-invasive techniques. We would like to investigate if the results of the bronchoscopy are comparable with results from the nose swab…
To determine pre-existing virus neutralization titer levels against RSV in a general healthy population (immunogenicity is a secondary study objective (proof-of concept) in the main phase I study).
The purpose of this study is to test the impact of a physical activity promotion program which is a personalized, semi-automated, coaching program utilizing an smartphone on which an app is installed and coaching by the investigator. The automated…
The main objective of this study is the clinical, physiological and psychosocial determinants of CAT in a broad sample of patients with moderate to very severe COPD and the impact of co-morbidities on the HRQL assessed with CAT. Secondary objectives…
To investigate the direct effect of caffeine on the respiratory effort of the preterm infant at birth.
Primary objective:The primary objective is to answer the question: How do COPD patients experience intensive care unit admission because of exacerbation and what is the impact on their quality of life. This study aims to understand the perspective…
Primary objective: * To study differences in global lung aeration before and during spontaneous breathing during mechanical ventilationSecondary objective:* To study the work of breathing (WOB) under various pressure support (PS) levels in…
The aim of this research is to gain a more detailed insight into the illness perceptions of patients with lung cancer. With this insight it is our aim to improve biopsychosocial care for these patients. Research question: What are the illness…
The purpose of this study is to explore and expand the understanding of the patient's experience of physical limitations in COPD from the perspective of the patient. The information will be used to support the development of a conceptual model…
In this study we want to investigate the effects of sustained hyperglycaemia and hypoxia on the hypoxic pulmonary vasoconstriction and hypoxic ventilatory response
The development of a disease specific questionnaire to measure the quality of life in children with BPD at age 4-8, that can be answered by the parents.
The objective of this study is to evaluate the reproducibility (CV) of a 6-minute cycle exercise performance test in patients with COPD.
to assess patient's overall preference for the two inhaler devices in COPD patients after 2 weeks of dialy practice.
Determine arm and shoulder function and quality of life scores before and after treatment of SST. The untreated extremity can serve as a control.Determine riskfactors for a poor functionale outcome and quality of life after treatment for SST (e.g.…
What is the prevalence of depression and anxiety in children with asthma. Is this more frequent in asthma than in other chronic conditions like diabetes and Coelikie? And how compares this to healthy children in the same phase of life?
We hypothesize a lung*protective mechanical ventilation using lower tidal volumes during general anesthesia for minimally invasive transthoracic esophagectomy to protect against postoperative pulmonary complications in patients undergoing minimally…
We propose to develop a multicenter registry of sarcoidosis associated pulmonary hypertension (SAPH). With this registry, we will characterize the demographics, clinical course, hemodynamics, pulmonary physiology, and disease management of…