112 results
Primary objective: to assess the inhibition of allergic responses of a single dose of subcutaneously (SC) administered REGN1908-1909 as measured by total nasal symptom score (TNSS), visual analog scale (VAS) nasal symptoms score, and peak nasal…
Demonstrate the safety and efficacy of ventilation with Ventrain® during 5 minutes. Safety is demonstrated if the peak pressure during insufflation does not exceed 25 cm H2O and PEEP (Positive End Expiratory Pressure) is not smaller than -5 cm H2O…
Investigate the prevalence of rhinosinusitis and/or nasal polyps in adult patients with Cystic Fibrosis. Also several aspects of sinonasal disease are investigated; quality of life, correlation between phenotype and genotype, microbiology, anatomy…
This Phase II trial aims to:1 Test the predictive value of Zr89 Cetuximab uptake in vivo for treatment specific outcome 2 Explore the impact of dose redistribution on loco-regional control and disease free survival.If individualized treatment…
In this study the relation of OSAS with functional status and cognition, and the effect of treatment with CPAP on outcomes of rehabilitation in stroke patients will be investigated. The main research questions are: 1) Is there a relationship between…
The aim of this study is to estimate the prevalence of late-onset inherited Pompe disease in a large cohort of patients with recently diagnosed obstructive sleep apnea syndrome (OSAS) in two different centres across Europe.
In this study the effect of SAS and the treatment with CPAP on cognitive functioning, fatigue and mood in stroke patients will be investigated. The main research questions are: 1) Is there a relationship between (the severity of) SAS and cognitive…
1. To investigate whether an adjusted mode of APAP can improve patients adherence in comparison to fixed CPAP in present-day PAP therapy of OSAHS patients.2. To investigate the agreement between the parameters of the CPAP devices and the polygraphy…
The aim of the project is to improve adherence to inhaled corticosteroids in children with asthma by using a Real-Time Medication Monitoring system (RTMM) and SMS alerts and to study weather improved adherence has an effect on asthma control and…
Primary Objective(s):Find the best 2 or 3 step strategy for screening of OSAS in a Dutch employee population to optimize a large scale screening program. Home PSG with the ALICE PDX, combined with answers on sleepiness, is the gold standard. This…
1. To assess prevalence of SAS in a Dutch chronic heart failure (CHF) population. 2. To assess whether there are group differences between CHF-patients without SAS and CHF-patients with SAS (OSAS and CSAS). 3. To assess the validity of the ApneaLink…
The purpose of this pilot study is to evaluate the feasibility, efficacy, safety of and patients* compliance to an OA-CPAP for planning a main randomised controlled study. The main objective is to investigate if a patient is treated effective,…
To assess the efficacy of reducing the sleep time in supine posture with positional therapy using the Z-cushion compared to compared to delay of treatment in patients with mild and moderate positional OSAS.
Measuring the forces exerted on upper en lower teeth during classic (direct) and (indirect) (video)laryngoscopy.
We want to determine if epiglottic downfolding leads to a better view of the glottis and more successful intubations. We also want to investigate if this comes at the cost of more postoperative sore throat, dysphonia, dysphagia and coughing…
The clinical response will be measured in allergic and non-allergic rhinitis patients and healthy participants. This will be done by means of symptom scores: visual analogue score (VAS) and rhinitis symptome score (RSS) and by means of measuring…
- To investigate the cause of the symptoms patients with a vagus nerve stimulator experience during exercise.- To investigate whether there are changes in EEG during stimulation.
Measuring the space on the right side of the videolaryngoscope blade and the palatopharyngeal wall in a cohort of ASA I-III patients with a normal mouth opening (Mallampati I, II and III). We also want to investigate how this space differs from the…
What is the effectiveness of septoplasty compared to a watchful waiting strategy in adults interms of health related quality of life and nasal passage? What is the relation between costs and effects of this procedure?Which patients benefit most from…
The primary objective of this study is to analyze synchrony between ventilator and upper airways in COPD patients.Secondary objectives are to investigate whether the level of support and the triggering mode of noninvasive ventilation induces or…