112 results
Primary aim is to study electronically measured compliance to inhaled corticosteroids (ICS) in a multicultural population of children with asthma in Amsterdam. A secondary aim will be to compare electronical data on compliance with parent reports.
Het bestuderen en vergelijken van cocaïne, tetracaïne-oxymetazoline en ropivacaïne-oxymetazoline wat betreft de peroperatieve decongestie en hemostasis en postoperatieve analgesie die zij bieden bij FESS. Study and compare the peroperative…
Analyze the correlation between change in EELV with change in MIF¬50
1. To integrate ENT specialists into the GA²LEN project in co-operations with internal medicine, allergists and pneumologists.2. To characterize patients with upper airway diseases on the basis of clinical parameters, infectious agents, inflammatory…
1. To investigate whether the currently used hay fever forecast correlates with the symptoms that grass pollen allergic patients report directly using a new communication system that allows direct control, and whether the model can be improved.2.…
PRIMARY OBJECTIVES * To evaluate the efficacy of lebrikizumab compared with placebo as measured by theability of patients to achieve lower daily doses of OCS while maintaining control oftheir asthma* To evaluate periostin as a predictive biomarker…
To compare the cost-effectiveness and effectiveness of MRA therapy versus CPAP therapy in patients with moderate OSAS.
To investigate the changes in facial- and hand analysis in patients with acromegaly as a result of medical treatment and pituitary surgery, and to investigate the changes in relational proportions between facial- and hand structures, incidence and…
To identify biomarkers associated with OSA in bariatric surgery patients prior to surgery; to investigate the effect of bariatric surgery on these with OSA associated biomarkers; to identify biomarkers that predict amelioration of OSA after…
Primary ObjectiveTo determine the influence of treatment for OSA opioid-induced respiratory depression (minute ventilation (Vi); tidal volume (Vt); respiratory rate (RR); end-tidal pCO2; SpO2).Secondary ObjectivesAim 2: To determine the influence of…
Nasal mucus proteins have different origins and production sites and gene expression does not necessarily result in functional metabolites. The aim of this proposed project is to try and analyze in a holistic proteomic approach the response to…
We found a prevalence of 6% sensitization in patients with a possible food allergy. The aim of this study is to investigate if sensitization to lupine flour in atopic patients has clinical relevance. Additionally, we want to investigate if cross-…
The objective of this study is to improve the understanding of subjective cognitive complaints expressed by patients with OSAS by:1. Comparing subjective cognitive complaints of patients with OSAS to healthy controls2. Studying the effect of…
The main purpose of this study is to examine the effects of expiratory muscle strength training (EMST) in subjects who have undergone a total laryngectomy. In this pilot study outcomes in pulmonary function, functional exercise capacity, vocal…
Current practice variance in adult patients with chronic rhinosinusitis with nasal polyps (CRSwNP) is not efficient. Endoscopicsinus surgery (ESS) is the most common ENT operation in adults in the Netherlands. The objective of the present study is…
Primary Objective: Evaluation of effectiveness (AHI using PSG) of SPT when compared to MRA in patients with mild to moderate positional dependent obstructive sleep apnea (POSA) in a non-inferiority setting for a short (3 months) and longterm (12…
The overall aim of the study is to correlate the anatomical and functional anatomy of the larynx, as seen on MRI to various functional outcome measures in patients who underwent open airway surgery for LTS. The specific aims of this study are: 1) to…
Secondary objectives:The secondary objectives include demonstration of clinical efficacy of SCIT with BM41 alone, with BM41 plus VD3 and with VD3 alone, all three compared to placebo. Efficacy will be analysed for the upper airways by titrated nasal…
The aim of this clinical phase IIa randomized, double-blind, placebo-controlled study is to investigate tolerability/ safety and clinical and immunological effects of the addition of a subcuteaneous injection of a VD3 analogue in the vicinity of the…