16 results
Primary Objective: To prospectively assess the impact and relevance of several risk factors for SAA/acute wheeze that have been identified in retrospective studies, including our own. Secondary Objective: To assess short-term medical and…
Primary Objective: The aim of the present study is to investigate whether home initiation of chronic NIV in stable COPD patients with CHRF is non-inferior to inpatient initiation Secondary Objective(s): The secondary objective of the study is to…
To assess the efficacy of a loading dose of intravenous salbutamol in children admitted to a PICU for severe acute wheeze or severe acute asthma. Efficacy is measured by the reduction in asthma score (Qureshi) at 1 hour after administration of the…
The main objective of the panel study is to evaluate the associations between short-term variation of concentrations of key air pollutants (NO2, PM2.5, PM10, and ultrafine particles), measured on a fine spatial and temporal resolution, and short-…
To assess the immunological efficacy of four-month treatment of omalizumab in patients with non-atopic asthma compared to patients with allergic asthma
To diminish the number of asthma exacerbations with the regular use of a bacterial lysate.
The aim of this study is to evaluate the metabolic load during a single session of moderate intensity walking in water compared to walking on land (over-ground) in people with COPD who are normal weight and obese, compared with peak exercise…
Present and evaluate a novel monitoring system for 24/7 continuously monitoring of COPD patients, using cHealth technologies.
The primary outcome of the study is a 50% reduction in exacerbation rate in patients using TIS once daily (OD). Secondary outcome parameters are lung function (FEV1, FVC), QoL (QOL-B), LTRI-VAS, Leicester cough score), bacterial load in sputum and…
Primary:To evaluate the effects of FF/UMEC/VI on lung function compared with FF/VI after 24 weeks of treatmentSecondary:To assess the efficacy (exacerbations), FEV1 3h post dose, asthma symptoms, safety and tolerability.
Primary:To assess the use of mepolizumab in safety syringe for the subcutaneous self-administration of mepolizumab by subjects with severe eosinophilic asthma.Secondary:To assess the use of mepolizumab in safety syringe outside the clinic setting.…
Primary:To compare the number of critical errors made by COPD patients, after a subject has read the respective patient information leaflet(s) (PIL), for each treatment option tested.Secondary:Number of critical errors made after instruction from…
-To determine the presence of changes in the retinal microvasculature and endothelial function in patients with COPD (part 1) -To determine the effect of physical exercise on microvasculare reactivity in patients with COPD and the effect of…
1) To collect continuous data2) To extract and describe features, patterns and relationships in the data3) To quantify relationships between vital signs and activity variables or exposure to air pollution4) To identify features, patterns and…
To determine: 1) baseline platelet activation, 2) platelet responses to stimulation with different platelet agonists, 3) formation of platelet-monocyte complexes), 4) effects on plasmatic coagulation, 5) soluble markers of platelet activation and…
This study aims to investigate if there is a correlation between the severity of bronchoconstriction after an exercise challenge test 6h after a single dose of Qvar and after 4 weeks of treatment with Qvar, in order to know if the respons to a…