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Influence of hyperglycaemia and sustained hypoxia on the hypoxic ventilatory response and the hypoxic pulmonary vasoconstriction.

In this study we want to investigate the effects of sustained hyperglycaemia and hypoxia on the hypoxic pulmonary vasoconstriction and hypoxic ventilatory response

Registry of Sarcoidosis Associated Pulmonary Hypertension (RESAPH)

We propose to develop a multicenter registry of sarcoidosis associated pulmonary hypertension (SAPH). With this registry, we will characterize the demographics, clinical course, hemodynamics, pulmonary physiology, and disease management of…

Efficacy and safety of home treatment versus in hospital treatment with LMWH in patients with non-massive pulmonary embolism

1. To evaluate the efficacy and safety of out of hospital treatment with LMWH and Vitamin K antagonists in consecutive patients with objectively proven acute non-massive pulmonary embolism2. To perform a health economics evaluation in all patients3…

Quantification of pulmonary vascular remodelling in pulmonary arterial hypertension patients using positron emission tomography

To non-invasively quantify pulmonary vascular remodeling in pulmonary arterial hypertension using [18F]-FLT (determination hyperproliferation).

Implementation and effect of exercise and respiratory training on 6-minute walking distance in patients with severe chronic pulmonary hypertension: a randomized controlled multicenter trial in European countries

The aim of this study is to guide European PH-centers to become specialized centers for training in PH. This approach is in line with European PH-guidelines [12] which classified the exercise training in specialized centers with a closely monitored…

68Ga PET/CT versus 99mTc SPECT/CT for lung perfusion and ventilation scintigraphy; a technical and practical feasibility study

To investigate and define the most optimal technical acquisition parameters for V/Q PET/CT