58 results
Determine the existence of a relation between GER and apnea and their underlying mechanisms, in infants *37 weeks * 12 months.
Is to identify the incidence and prevalende of PH in premature born infants. In addition we will identify possible risk factors for the development of PH and we want to determine the prognosis and survival of these patients. PrimaryTo determine the…
To assess the accuracy and cost-effectiveness of PO screening for CCHD in the Dutch perinatal care system.
To describe the synchronicity of nIPPV respiratory support with spontaneous diaphragm activity and the effect of asynchrony of mechanical inflations and spontaneous breaths on lung volume, mechanical parameters and diaphragm activity in preterm…
To identify alternative dEMG electrode positions in preterm infants for cardio-respiratory monitoring.
Recently, population PK/PD modeling and simulation studies have enabled the development of evidence-based individualized dosing schemes for children with a limited number of subjects, thus improving drug safety and efficacy. The application of PK/PD…
Primary objective: -to determine if there is a significant difference in the incidence of oxygen dependency at day 28 and/or death within the first 28 days of life between newborns with congenital diaphragmatic hernia treated with high frequency…
The development of a disease specific questionnaire to measure the quality of life in children with BPD at age 4-8, that can be answered by the parents.
The primary objective is to determine if echocardiography in combination with plasma biomarkers can be used as a potential predictor for pulmonary hypertension. The secondary objectives are assessment of a potential correlation between…
1. Feasibility and reproducibility of transcutaneous (tc) dEMG on premature neonates. - Are the signal quality (heart rate and respiratory rate), bradycardias and apneas similar to the current impedance monitoring2. Can we differentiate between…
The objective of this study is to obtain physiological data on lung aeration during pulmonary transition in newborn infants.
The primary objective of this study will be to evaluate the cardiac adaptation due to hemodynamic changes in monochorionic twin pregnancies complicated by TTTS and sIUGR, by evaluating the size and the growth pattern of the pulmonary artery and the…
To investigate the direct effect of caffeine on the respiratory effort of the preterm infant at birth.
Main question: What is the lung function of late preterm births compared with children born at term at age 12? Sub-questions: - Which respiratory symptoms in late preterm infants at age 12?
Objective: to obtain lung function parameters in infants born preterm at the age of 6 months and to evaluate risk factors for impaired lung function
To study whether microcirculatory perfusion is improved by ECMO. Perfusion will be studied before & after ECMO start, during ECMO weaning and before & after ECMO stop. To study the precictive value of perfusion and its correlation…
The aim of this study is to test the hypothesis that using nasal tube as interface during resuscitation/stabilisation of preterm infants at birth is more effective compared to mask.
Does the use of NIPPV in ELBW infants (<30 wks of GA and BW<1000gr) requiring non-intubated respiratory support in a Level III perinatal center increase the rate of survival without BPD when compared to nCPAP.
The main objective of this study is to determine if Low-Flow is non inferior in reducing apneic spells compared to caffeine. Secondary objectives are investigating if these treatments have an effect on the need of supplemental ventilation and on the…
Aim of total study:Diagnosing all components of RS in an objective mannerAim of present substudy:Increasing the reliability and decreasing the burden of the method with which glossoptosis can be determined in newborns with RS