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The PHENOSAR trial: Antibiotic treatment of biopsy confirmed phenotypes in sarcoidosis: a proof of concept clinical trial

This study has been transitioned to CTIS with ID 2024-513534-38-00 check the CTIS register for the current data. Investigate whether treatment with azithromycin has an inhibitory effect on the mTOR pathway and/or C. acnes, causing a reduction of the…

Development of a *two hit* in vivo autologous platelet transfusion model in healthy volunteers

To develop a *two hit* in vivo autologous PLTs transfusion model in healthy male volunteers

A NOVEL observational longiTudinal studY on patients with a diagnosis or
suspected diagnosis of asthma and/or COPD to describe patient
characteristics, treatment patterns and the burden of illness over time and
to identify phenotypes and endotypes associated with differential outcomes
that may support future development of personalised treatment strategies

The primary objectives are:*To describe patient characteristics, treatment patterns and the burden of illness over time for individuals in clinical practice with a diagnosis, or suspected diagnosis,2of asthma and/or COPD. Data will be described for…

Phenotyping and classifying of childhood and adult asthma exacerbations: towards future personalised treatment. An observational multicentre study.

The primary objective of the study is to determine the relationship between exacerbation treatment response at day 7 and the phenotypical characteristics of asthma exacerbations. Secondary objectives are 1) developing a prediction model based on…