5 results
Our main aim is to validate the TiMaSCAN as both a diagnostic and monitoring tool in the treatment of pulmonary exacerbations in CF patients.
This study aims to evaluate the PK profile and IIV of drug exposure in plasma in children (aged 6-17 years) receiving (elexacaftor-)tezacaftor-ivacaftor. Secondary objectives are to evaluate the relationship between covariates and PK parameters that…
Primary Objectives: To investigate the pharmacokinetic interaction of elexacaftor/tezacaftor/ivacaftor and tacrolimus in adult CF patients using tacrolimus after renal or liver transplantation by:- quantitating the effect of elexacaftor/tezacaftor/…
• To perform full kinetic modeling of [18F]F-AraG for the uptake in tumor lesions and healthy organs (e.g. spleen) by exploring different kinetic models and outcome measures as well as its test-retest (TRT) variability to guide the selection of an…
Our overall aim is to assess the seroprevalence of SARS-CoV-2 antibodies in an international population of pwCF and to examine associations between SARS-CoV-2 infection and clinical risk factors for infection, as well as subsequent clinical outcomes…