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Effects of changes in global blood flow on mean systemic filling pressure and heart performance.

To predict the influence of PEEP on Pms and eH.

Range-Finding and Pilot Study For: Extended Fragrance Ingredients Surveillance Study (EFISS) - Surveillance Study to Monitor the Frequency of Contact Allergy to a Defined Group of Fragrance Ingredients with a View to Providing Reliable Information on Trends

To design an industry-sponsored surveillance study incorporating both additional and existing materials that has the possibility of identifying trends in the incidence of skin contact allergy.

The Prevalence of contact Allergies for wound dressings In patients with Diabetic foot ulcers.

The primary objective of this study is to determine the prevalence of contact allergies in patients with diabetic foot ulcers.

The effect of explantation of silicone breast implants on neuroimages of the brain in ASIA-syndrome patients: a pilot fMRI-study

To investigate the effect of explantation of silicone breast implants on neuroimaging of the brain (fMRI) in ASIA syndrome patients to gain more insight in the neurophysiological basis and nociceptive system of ASIA syndrome due to SIIS and the…

Evaluation of a non-invasive dynamic light scattering sensor for the measurement of heart rate in neonates.

Our primary objective is to correlate the measured heart rates between ECG measurements and the Elfi-Tech dynamic light scattering sensor.

Clinical evaluation of a new tcPCO2 sensor in neonates: A pilot study.

The primary objective of this pilot study is to determine the technical feasibility of the sensor in clinical practice. Accuracy is investigated with an agreement analysis of transcutaneous measurements and standard of care blood sampling,…

Detection of neonatal sepsis with non-invasive transcutaneous blood gas monitoring

The primary objective of this study is to determine the relation of delta PO2 (PaO2-tcPO2) and delta PCO2 (tcPCO2-cPCO2) levels to sepsis. The secondary aims are to determine the factors that influence delta PO2 and delta PCO2 and to determine the…

Dose range finding pilot study for diagnostic patch testing with ME-PPD

Primary Objective: Pilot study to identify the optimal patch test concentration for detecting contact allergy to ME-PPD in subjects with a proven contact allergy to PPD, who may be allergic to ME-PPD. Hypothesis: In this study subjects will be…

Visibility of standardized induced bruises under forensic light source compared to white light source.

To assess visibility of standardized induced bruises using imaging (photography) under white light, forensic light sources, and multispectral scanning, at set time intervals.To gain understanding in the influence of individual factors on bruising.

The effect of Virtual Reality on pain in patients undergoing lumbar puncture. A randomized controlled trial

The aim of this study is to determine whether VR used during lumbar puncture will significantly reduce pain and anxiety perception.

Extended Fragrance Ingredients Surveillance Study (EFISS) - Surveillance Study to Monitor the Frequency of Contact Allergy to a Defined Group of Fragrance Ingredients with a View to Providing Reliable Information onTrends

Primary Objective:Identify trends in the incidence of skin contact allergy with particular reference to fragrance materials that have not hitherto beentested on a systematic basis.Secondary Objective(s):A subsidiary objective is to gather data on…

Comparative evaluation of body temperature measurement and invasive temperature monitoring in an intensive care setting

This study*s research objective is to investigate the validity of BT measurement through skin temperature and skin heat flux measurement by the Corsano CardioWatch 287-2 against invasive rectal body temperature monitoring devices in a clinical…