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Wound closure with OptiClose® System after median sternotomy - pilot study

Comparing the OptiClose® System with traditional skin wound closure with intracutaneous sutures on wound closing time, patient comfort, cosmetic results, surgical handling, and costs.

Biomarkers for soft tissue damage in a rigid and a soft-layered spineboard

In this study we want to investigate if there are differences in cytokine and mFABp production when using a rigid and a soft-layered spineboard, in relation to tissue-interface pressures. Furthermore, redness of the skin and experienced comfort are…

A randomized, double-blind, placebo-controlled, serial-cohort, single ascending dose of Xen2174 with bupivacaine interaction study administered intrathecally in healthy volunteers.

The objectives of the study are:To determine the pharmacokinetic and pharmacodynamic interaction of a single ascending dose of Xen2174 with bupivacaine, and in one cohort of Xen2174 alone, when administered intrathecally to healthy volunteers and…

A randomized, double-blind, placebo-controlled, serial-cohort, single ascending dose of Xen2174 PK/PD study administered intrathecally in healthy volunteers.

The objectives of the study are:To determine the pharmacokinetic profile of Xen2174 in plasma and CSF when administered intrathecally to healthy volunteersTo determine which modalities of pain are affected by treatment with Xen2174 when administered…

Wountherapy in patienten with a sinus pilonidalis using a VAC-therapie versus Kerlix-gauze.

To show the differrence of total healing of wound between two therapies, VAC and gauze-therapy, in patient with a sinu pilonidalis after chirgical intervention.

Evaluation of a physical therapy management program aimed at functional restoration for people with chronic complex regional pain syndrome type 1 of the lower extremity.

Aim of the study is to describe and evaluate an alternative physical therapy management program in patients with a complex regional pain syndrome type 1. A secondary aim is to describe the adverse effects that occur during or after the intervention.