44 results
Systematic gathering of biomaterial and phenotypic data of IBD patients during clinical care provides assessment of molecular markers in the DNA, the transcriptome and proteome. The markers can be associated with the different disease phenotypes…
The current project has two goals: (1) to measure viewing strategies used by children with normal vision, children with ocular visual impairment and children with CVI and (2) to evaluate whether training viewing strategies results in more efficient…
Main objectivesCohort study:To investigate the prognostic implications of skin sodium accumulation for CKD patients.Sodium excretion intervention study:To study the effect of increased renal sodium excretion, with and without …
The primary objective of the pilot study is to assess the feasibility of a definitive trial to determine the effect of arthroscopic soft tissue stabilization vs. non-surgical treatment on rates of recurrent anterior …
To develop a FOG prediction algorithm under free-living conditions, and to test evaluate the use of the Parkinson's Vibrating socks under the same conditions
To assess the impact of a nutritional formulation containing caprylic acid and omega 3 fatty acids on skeletal muscle function recovery from damaging exercise.
To compare the objective response rate between patients with metastatic non-small cell lung cancer characterized by PDL-1 TPS<50% and low TMB and either actionable mutation, inactivating STK11, KEAP1 or NFE2L2 mutations, treated by…
Primary Objectives:Associated pharmaceutical trial:To compare the efficacy of disitamab vedotin in combination with pembrolizumab to chemotherapy as first-line treatment in participants with advanced UC that expresses HER2Clinical…
Better knowledge of the clinical phenotype/natural history and genotype of Traboulsi Syndrome.
In this study, we investigate the possibility of preoperatively estimating the risk of complications in patients using the FitMáx, VSAQ, and PREOP checklist. These questionnaires are automatically administered via the Mijn MMC patient portal two…
Primary Objective: To develop and validate a knowledge questionnaire as an improved version of our RAK-Q 1.0 (phase 1 and 2). Afterwards we will create a CAT (phase 3).
This study aims to determine the effect of real-time symptom monitoring on HRQoL in patients with mBC who start first-line chemo(immune)therapy. Further objectives include analyzing the effect of PRS monitoring on physical functioning, the severity…
The primary objective is to show that brain MRI surveillance alone is non-inferior in terms of overall survival (OS) to brain MRI surveillance combined with prophylactic cranial irradiation (PCI) for the treatment of small cell lung cancer (SCLC).
Objective 1: To assess the effect of implementation of a dashboard, with (near) real-time data feedback of risk stratification tools and care processes, on relevant clinical outcomes (in-hospital mortality, ED-LOS, admission rate) and discrepancy…
The aim of this study is to objectively determine physical activity levels and to explore factors associated with the level of physical activity during hospital admission in hospitalized children between six months and 18 years old.
The primary aim of this study is to investigate the effect of four different degrees of arch support on arch compression and running economy. Moreover, as a secondary aim, this study also examines the effect of bending location on running economy.…
To assess the association between time-in-range blood pressure measurements and the risk of developing preeclampsia in women with hypertensive disorders of pregnancy. To evaluate the relationship between time-in-range blood pressure and gestational…
This research's goal is to develop an artificial intelligence (AI) model that can predict when a child is at risk of experiencing an asthma exacerbation and what their personal risk factors are. The model should be both accurate and…
How do middle-aged people in the northern Netherlands, both with and without a migration background, prepare for aging, and what support do they need?
The primary objective of this research is to assess the occurrence, variability and underlying causes of treating pediatric patients with respiratory infections at the ED. This is done in order to identify and ultimately de-implement ineffective…