20 results
Systematic gathering of biomaterial and phenotypic data of IBD patients during clinical care provides assessment of molecular markers in the DNA, the transcriptome and proteome. The markers can be associated with the different disease phenotypes…
Subgroup 1 (complex appendicitis without mass and/or abscess formation): LA is associated with reduced superficial site infections, shorter length of stay, less costs, less pain, and better hr-QoL, compared with OA without compromising overall…
The primary aim of this split-mouth randomized clinical trial is to assess accuracy of bracket positioning of a fully digital IDB workflow compared to a DBB workflow, with IDB bracket planning serving as reference for both methods. The secondary…
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Objective: The primary objective of the study is determining the contributing factors in bracing for AIS. The contributing factors are determined as factors of influence in the corrective possibilities and therefore end term…
Bone-anchored maxillary protraction therapy improves facial profile in cleft children.
We aim to identify immunological parameters during (immune)therapy. We will study the effect of (immune)therapy on generic immune mediators and more specifically for NK cell, T effector and Treg cell functionality. Furthermore, we will explore DNX…
This study evaluates the efficacy and applicability of schema therapy for anorexia nervosa.
Our objective is to compare the efficacy of early chest tube removal combined with single-shot PVB versus standard treatment (chest tube for at least 3 days and thoracic epidural analgesia (TEA)) after surgery for PSP. Efficacy is defined as…
Primary Objectives:Associated pharmaceutical trial:To compare the efficacy of disitamab vedotin in combination with pembrolizumab to chemotherapy as first-line treatment in participants with advanced UC that expresses HER2Clinical…
The objective of this study is to establish the clinical performance of VENTANA PD-L1 (SP263) CDx Assay as a companion diagnostic (CDx) for the identification of patients with NSCLC who may benefit from treatment with [redacted]. …
This study has two objectives. First, to evaluate the measurement properties (construct validity, internal consistency, and responsiveness) of five different PROMs in the ED. These PROMs include the Quality of Recovery (QoR-15) scale, the Brief…
Objective 1: To assess the effect of implementation of a dashboard, with (near) real-time data feedback of risk stratification tools and care processes, on relevant clinical outcomes (in-hospital mortality, ED-LOS, admission rate) and discrepancy…
The aim of this study is to objectively determine physical activity levels and to explore factors associated with the level of physical activity during hospital admission in hospitalized children between six months and 18 years old.
To assess the association between time-in-range blood pressure measurements and the risk of developing preeclampsia in women with hypertensive disorders of pregnancy. To evaluate the relationship between time-in-range blood pressure and gestational…
In this study we aim to understand if (personalized) parenting tips strengthen parenting (e.g.: more structure, autonomy support, relatedness, less overparenting) and improve adolescent well-being (e.g.: higher life satisfaction, lower symptoms of…
The primary objective of this research is to assess the occurrence, variability and underlying causes of treating pediatric patients with respiratory infections at the ED. This is done in order to identify and ultimately de-implement ineffective…
The aim of the study is to look retrospectively at all children who presented with high-energy trauma at the Amsterdam UMC in the past five years, how this research was conducted and what findings were noted. In addition, we want to draw up a…
MAIN GOAL: We will integrate population-level registry (CBS) data and data from a survey on beliefs, values, and behavior to build a model to predict SARS-CoV-2 vaccination uptake on a population and local level. This model will take into account…
The aim of this study is to develop a Dutch adaptation and translation of the User Satisfaction Evaluation Questionnaire (USEQ), for measuring user satisfaction and usability in a Dutch pediatric population (6-18 years old), and to determine its…