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The study will help us to determine 1. the necessary type of (combined) examinations and 2. the sample size that is essential to evaluate (future) genetic therapy in Usher syndrome type 2 and USH2A associated nsRP.
The primary objective of this study is to evaluate the diagnostic accuracy of physical examination and ultrasound to identify active synovial proliferation in haemophilia patients with subclinical synovial proliferation. The secondary…
Better knowledge of the clinical phenotype/natural history and genotype of Traboulsi Syndrome.
In this study, we investigate the possibility of preoperatively estimating the risk of complications in patients using the FitMáx, VSAQ, and PREOP checklist. These questionnaires are automatically administered via the Mijn MMC patient portal two…
Primary Objective: To develop and validate a knowledge questionnaire as an improved version of our RAK-Q 1.0 (phase 1 and 2). Afterwards we will create a CAT (phase 3).
Whole genome comparison between microorganisms cultured from PJI and those cultured from preoperative swabs of the patients’ microbiome, to determine the origin of the infection.
To assess inter-individual and intra-individual variation in objective skin pigmentation measurement using non-invasive colorimetry and multispectral imaging in healthy individuals and patients with skin disease.
In a previous study, the validity of the FitMáx© in measuring physical condition was examined in comparison to the gold standard—an exertion test with breath gas analysis. The aim of the current follow-up study is to improve the international…
This study has two objectives. First, to evaluate the measurement properties (construct validity, internal consistency, and responsiveness) of five different PROMs in the ED. These PROMs include the Quality of Recovery (QoR-15) scale, the Brief…
Objective 1: To assess the effect of implementation of a dashboard, with (near) real-time data feedback of risk stratification tools and care processes, on relevant clinical outcomes (in-hospital mortality, ED-LOS, admission rate) and discrepancy…
The aim of this study is to objectively determine physical activity levels and to explore factors associated with the level of physical activity during hospital admission in hospitalized children between six months and 18 years old.
The primary aim of this study is to investigate the effect of four different degrees of arch support on arch compression and running economy. Moreover, as a secondary aim, this study also examines the effect of bending location on running economy.…
To assess the association between time-in-range blood pressure measurements and the risk of developing preeclampsia in women with hypertensive disorders of pregnancy. To evaluate the relationship between time-in-range blood pressure and gestational…
This research's goal is to develop an artificial intelligence (AI) model that can predict when a child is at risk of experiencing an asthma exacerbation and what their personal risk factors are. The model should be both accurate and…
In this study we aim to understand if (personalized) parenting tips strengthen parenting (e.g.: more structure, autonomy support, relatedness, less overparenting) and improve adolescent well-being (e.g.: higher life satisfaction, lower symptoms of…
How do middle-aged people in the northern Netherlands, both with and without a migration background, prepare for aging, and what support do they need?
The primary objective of this study is to isolate effects of dopamine receptor manipulation on distinct forms of working memory (WM) gating and their associated physiological changes in distinct layers of prefrontal cortex (measured with high-…
The primary objective of this research is to assess the occurrence, variability and underlying causes of treating pediatric patients with respiratory infections at the ED. This is done in order to identify and ultimately de-implement ineffective…
The purpose of this protocol amendment is to meet the current and future needs of the MacTel Project’s collaborating investigators and continue meeting initial objectives. In addition, a third objective is to understand the mechanisms involved in…
In this study we analyse the trends in new diagnoses for acute and chronic HBV and HCV in the Public Health Service (PHS) region of Amsterdam. In addition, we provide an overview of recent migration patterns and testing provision in the PHS region…