56 results
In patients diagnosed with a hip fracture who also have acute myocardial injury on presentation to hospital, is accelerated surgery superior to standard care for the primary outcome of death at 90 days after randomization?
The primary objective of the pilot study is to assess the feasibility of a definitive trial to determine the effect of arthroscopic soft tissue stabilization vs. non-surgical treatment on rates of recurrent anterior …
The primary aim of the proposed study is to evaluate the effectiveness (1) and cost-effectiveness (2) of a DST for patients with anxiety and/or mood disorders in comparison to UC.The secondary aims are: 3) to identify what works for whom by…
To develop a FOG prediction algorithm under free-living conditions, and to test evaluate the use of the Parkinson's Vibrating socks under the same conditions
To assess the impact of short-term forearm immobilization on forearm muscle glucose uptake and amino acid net balance and kinetics of individuals with T2D compared with a control group with normoglycaemia.
Primary objective• Assess the ability of donepezil to reverse biperiden-induced effects on adaptive tracking performance at timepoint 4h Secondary objectives• Evaluate the PK of donepezil and biperiden• Investigation of pro-cholinergic effects of…
To assess the impact of a nutritional formulation containing caprylic acid and omega 3 fatty acids on skeletal muscle function recovery from damaging exercise.
The primary objectives of this study are to evaluate the safety and effectiveness of a novel diagnostic approach applying PSA-density and MRI-imaging-based monitoring, as opposed to immediate prostate biopsy, in men with an intermediate risk of…
The main objective of this study is to establish a controlled human infection model for Chikungunya using the VLA1553 vaccine.Primary objectives:- To assess the infection rate induced by a single administration of the VLA1553 vaccine- To assess the…
The proposed study aims to develop a new dashboard (Wearalyze) and design a new user interface in co-creation with therapists, patients and experts in technology to enhance its usability and acceptability. In addition, we explore …
This study aims to determine the effect of real-time symptom monitoring on HRQoL in patients with mBC who start first-line chemo(immune)therapy. Further objectives include analyzing the effect of PRS monitoring on physical functioning, the severity…
Primary ObjectiveTo assess the safety, feasibility and frequency of relapsing P. vivax PvW1 infection after experimental sporozoite-administered Controlled Human Malaria Infection (CHMI)Secondary ObjectivesTo assess the immune response to primary…
This study aims to develop a RI using CTA-based CFD simulations for estimating the hemodynamic significance across mesenteric arterial stenoses (MAS).
The primary objective of this multicenter, observational study is to determine the incidence of chronic opioid use 30 days and 3 months after an initial opioid prescription at ED discharge. Secondary objectives include assessing the incidence of…
The aim of the study is to look retrospectively at all children who presented with high-energy trauma at the Amsterdam UMC in the past five years, how this research was conducted and what findings were noted. In addition, we want to draw up a…
The aim of this study is to investigate whether the social categorization process based on the patient’s gender (within this study only subdivided into cis-men and cis-women) affects the clinical evaluation, treatment of hyposexual sexual desire…
MAIN GOAL: We will integrate population-level registry (CBS) data and data from a survey on beliefs, values, and behavior to build a model to predict SARS-CoV-2 vaccination uptake on a population and local level. This model will take into account…
This study has two objectives. First, to evaluate the measurement properties (construct validity, internal consistency, and responsiveness) of five different PROMs in the ED. These PROMs include the Quality of Recovery (QoR-15) scale, the Brief…
Objective 1: To assess the effect of implementation of a dashboard, with (near) real-time data feedback of risk stratification tools and care processes, on relevant clinical outcomes (in-hospital mortality, ED-LOS, admission rate) and discrepancy…
The aim of this study is to objectively determine physical activity levels and to explore factors associated with the level of physical activity during hospital admission in hospitalized children between six months and 18 years old.