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The effect of Roux-en-Y gastric bypass on the rate and extent of absorption of metoprolol from a controlled release tablet in female bariatric patient volunteers: a single oral dose study before and after surgery

To investigate the effect of Roux-en-Y gastric bypass on the rate and extent of absorption of metoprolol and its main active metabolite α-OH metoprolol, after a single oral dose of 95 mg metoprolol CR tablet in 10 female bariatric surgery patient…