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Feasibility of holmium-166 microspheres for selective intra-tumoural treatment in head and neck cancer: biodistribution and safety in patients with malignancy of the oral cavity (the HIT study)

The main objective is to establish the feasibility of 166Ho-microspheres for intra-tumoural injections in OSCC by defining the total amount of leakage. The secondary objectives are to assess the safety profile by recording the adverse events, and…