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Establishing a Controlled Human Infection Model with the Chikungunya live attenuated vaccine VLA1553 in healthy volunteers

The main objective of this study is to establish a controlled human infection model for Chikungunya using the VLA1553 vaccine.Primary objectives:- To assess the infection rate induced by a single administration of the VLA1553 vaccine- To assess the…

An exploratory, multi-centre, two-part study to describe chronic induced urticaria characteristics and explore novel biomarkers with a multimodal patient profiling approach by comparing CIndU patients to chronic spontaneous urticaria patients and healthy volunteers

The objective of this study is to deep phenotype CIndU (subtype SD and ColdU) and detect novel biomarkers for diagnosis and treatment response as well as establish methodologies for (non-) invasive monitoring of treatment effects in chronic…

Validation of Tremor Assessment Software and Exploratory Sweat Lactate Analysis in Essential Tremor and Parkinson’s Disease

Primary Objectives: The primary objectives of this study are: To validate the performance of the Steady Hands software as a medical device in assessing hand tremor symptom intensity for Parkinson’s Disease (PD) and Essential Tremor (ET) by…