54 results
A clinical pilot-study were we will look if one time shock wave therapy on the distal radius leads to an increased bone mass. At the same time we would like to study if shock wave therapy of the distal radius could result in complications and we…
The primary aim of this study is to evaluate the feasibility, clinical effectiveness and cost effectiveness of a caregiver mediated exercises programme combined with e-health services (CARE4STROKE+) to improve self-reported health status and reduce…
1. Primary Objective:The primary objective is to evaluate the efficacy of Propeaq light therapy glasses with integrated blue LED lights on sleep disorders in patients with PD using the PSQI. 2. Secondary Objectives: The secondary objective of the…
To demonstrate that the use of US-accelerated catheter-derived thrombolysis in patients with recently (less than 7 weeks) thrombosed infra-inguinal bypass grafts or native arteries with half the dose urokinase (50.000 IU/h) will significantly reduce…
The specific aims for this study are to identify whether a structured exercise programme:a. is feasible for people with HD, in terms of adherence, process and safetyb. improves physical fitness in people with HDc. improves physical function and…
Primary ObjectiveThe primary objective of this study is to assess whether the antidepressant response to IV ketamine can be maintained by minocycline compared to placebo.Secondary ObjectivesThe secondary objectives of this study are:* To investigate…
The objective of this pilot randomized controlled trial (RCT) is to assess the feasibility and to determine the effect size of a physical activity/exercise program in improving objective cognitive functioning and reducing self-reported cognitive…
To evaluate the effect of parenteral supplementation of fishoil based emulsion (rich in omega-3 fatty acids) compared with a soy bean oil emulsion (rich in omega-6 fatty acids) on the leukocyte functions (amongst others production of TNF-α and other…
The main aim of the study is to investigate the influence of discussing religious issues during therapy on treatment outcome, both 6 months after start of treatment and 1,5 year after start of treatment. In addition, the study will take possible…
1. To characterize the efficacy of topical Fibrocaps plus gelatin sponge, as compared to gelatin sponge alone, in surgical subjects when control of mild to moderate bleeding by standard surgical techniques is ineffective and/or impractical2. To…
See also page 19 (section 6) of the protocol:6. Study ObjectiveIt is the objective of this study to assess vascular healing by Optical Coherence Tomography (OCT) analysis after deployment of the Abluminal Sirolimus Coated Bio-Engineered Stent (Combo…
Primary objective: To evaluate the differences in digestion and absorption on the administration of enteral nutrition either gastric or distal to the ligament of Treitz in the jejunum.Secondary objective: To evaluate the differences in endocrine…
Primary: To investigate the effects of 300 mg aliskiren on albuminuria in patients with non-diabeticnephropathy treated with ramipril 10 mg and volume intervention.Secundary: Effects of ramipril and ramipril plus aliskiren. Effects on RAAS…
This clinical trial is being performed to evaluate the efficacy of a single dose of TBS-2 on the occurence of orgasm. This study will explore the effect of TBS-2 on inducing an orgasm following sexual stimuli in anorgasmic female subjects at four…
The primary objective of this study is to demonstrate whether the MiStent Drug Eluting Coronary Stent System can safely and effectively improve coronary luminal diameter in patients with symptomatic ischemic heart disease due to discrete de novo…
The primary objective of this study is to evaluate tolerance of a new high-energy high-protein oral nutritional supplement compared to a commercially available high-energy high-protein oral nutritional supplement in elderly subjects in need of oral…
To develop a simplified HALO90 ablation protocol at the same energy level and with compared efficacy and safety as the current protocol.
The primary objective of this clinical trial is to demonstrate the safety and effectiveness of the Combo Bio-engineered Sirolimus Eluting Stent (Combo Stent) compared to the commercially available TAXUS® Liberté® Paclitaxel-Eluting Stent (DES) in…
Primary ObjectivesTo assess the change in inflammatory biomarkers in the synovial tissue of subjects with RA on a background of methotrexate after administration of a single, intravenous dose of GSK315234, as compared to placebo. To assess the…
This pilot study comprises two objectives.The size of this phase III trial and the choice for a specific primary outcome will depend on the sensitivity of the outcomes to differences, the design of the study and the statistical properties of the…