503 results
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
- Six weeks of ESM combined with personalized feedback sessions, compared with treatment as usual (TAU), leads to a stronger reduction in fatigue symptoms (primary outcome clinical effectiveness). - This intervention also leads to improvements in…
The proportion of successful patients, defined as an improvement in LARS category, will be 25% larger in the experimental group than in the control group (in which 10 % improvement is assumed).
To reduce the extent of healthy breast tissue resection by US-guided surgery for palpable tumours compared to traditional palpation-guided surgery, without compromising oncological principles. To improve cosmetic outcomes and quality of life by US-…
The primary aim of the trial is to assess what the optimal treatment regimen for acetylsalicylic acid, a statin and two BP-lowering agents is (administered as in regular care in individual agents, a fixed-dose combination pill administered in the…
Study 1: Examine how interparental and parent-child relationships in families who have experienced CSA differ from interparental and parent-child relationships in families who have not experienced CSA, and how these relational effects are related to…
The intended result is the discovery of an more effective, more simple, cheaper and more user-friendly treatment for positional OSA than current therapies. Positional therapies have been used as regular treatment in the Amsterdam Wake Sleep Center.…
Aim of this study is to determine the effectiveness of Extracorporeal Shockwave Therapy (ESWT) on degree of recovery after 3 months in patients with MTSS.
The main study objective is to determine the time to, as well as number of exacerbations of atopic dermatitis in the study period between the study groups A and B. The secondary objectives are the differences in transepidermal water loss and Quality…
The purpose of this study is to determine whether playing the computer game Tetris® prior to dental treatment is capable of reducing trait anxiety in patients suffering from a severe form of dental anxiety. Patients who visist a dental fear clinic…
The principal objective of this study will be to critically evaluate if the fMRI-neurofeedback training is successful in reducing ADHD symptoms and improving cognitive functioning. Thus, the first goal is to show that ADHD patients are able to…
Our primary objective is to examine the effects of two expectation manipulations (verbal suggestions with regard to an inert substance and an imagery exercise) on self-reported sensitivity to physical sensations of pain, itch, and fatigue.…
To determine which bowel preparation product is superior in cleansing the colon and in patient satisfaction.
To demonstrate non-inferiority in terms of neointimal coverage of Cre8 (CID) Drug Eluting Stent, evaluated at three months afterstent implantation, compared to Vision/Multilink 8 (Abbott) Bare Metal Stent evaluated at one month, in terms of…
The purpose of the present randomized controlled pilot study is to assess the efficacy, safety and practical aspects of autologous epidermal cell suspension grafting using ReCell in segmental vitiligo and piebaldism patients. Results of this study…
The main aim of the present study is i)To assess whether sugammadex has a positive effect on the post-operative alertness of the patients, and ii) to assess the nature, magnitude and the time of onset of this effect (if any).
Primary objective:To demonstrate that the mean change from baseline in Best Corrected Visual Acuity (BCVA) over a 12 month treatment period obtained with either a 0.5 mg ranibizumab *Treat and Extend* (TE) dosing regimen with adjunctive laser, and/…
Primary objective: To determine if a single dose of SRT2379 attenuates the inflammatory response in normal healthy male subjects after exposure to low-dose endotoxin (LPS) Secondary objectives: (1) To determine PK of SRT2379 in normal healthy male…
The primary objective of this study is to demonstrate whether the MiStent Drug Eluting Coronary Stent System can safely and effectively improve coronary luminal diameter in patients with symptomatic ischemic heart disease due to discrete de novo…
The primary objective of this study is to adjust the treatment protocol to specific cognitive problems related to Parkinson's disease and subsequently to evaluate the effectiveness of the protocol. Secundary objective is to get an overview of…