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Primary stability of cemented vs uncemented stems in revision total knee arthroplasty measured with RSA: a randomised controlled trial.

Which technique, cementing or press-fit implanting, of the tibial and femoral stem of the Legion revision total knee prosthesis provides the most primary stability?

Comparison of the everolimus eluting XIENCE-V* stent with the paclitaxel eluting TAXUS* stent in all-comers: a randomized open label study.

The main objective of the study is a head tot head comparison of the everolimus coated XIENCE-V* stent with the paclitaxel coated TAXUS* stent in order to observe whether there is a difference in clinical outcome between both stents. Efficacy of…

CEMENTED VERSUS NON CEMENTED HEMIARTHROPLASTY OF THE HIP AS A TREATMENT FOR A DISPLACED FEMORAL NECK FRACTURE; A RANDOMISED TRIAL

Objective: The main objectives of this study are technical and functional outcome of the hemiarthroplasty

Treatment in the Rotterdam Early Arthritis CoHort

5. Study objective(s) and hypothesis:The aim of this study is to assess the value of early, intensive and efficient treatment of patients with recent acquired arthritis, in preventing progression into destructive RA

Effect of a lower limb strength training program on physical functioning in children with cerebral palsy

The purpose of this study is to determine the effects of a strength training program on physical functioning in children with CP.

Optimal Stimulation Rates in Sacral Neuromodulation Therapy

To determine whether rate change is feasible and has a positive influence on the effect of SNS on the symptoms measured with voiding diaries.To investigate whether there are differences between optimal stimulation settings between patients with SNS…

Mirrortherapy for improving handfunction in chronic stage after stroke: a study on its effectiveness and an fMRI evaluation of underlying cortical mechanisms.

The study objective is to evaluate, with respect to hand function, the effect of a physical therapy program based on mirror therapy compared to conventional physical therapy in chronic stroke patients and to improve our understanding of the…

EPC quantification after G-CSF stimulation in healthy volunteers

Primary objective is:To determine whether a single subcutaneous injection of G-CSF induces an immediate (within six hours) release of bone marrow progenitor cells in healthy volunteers.

Distal Pancreatectomy
A randomized controlled trial to compare two different surgical techniques

A successfully conducted trial will have a positive impact on the future handling of thepancreatic remnant in distal pancreatectomy. The reliable and comparable data generated in this trial may support an evidence-based choice of a surgical…

Scorpio PS vs Scorpio NRG PS total knee arthroplasty. Comparative investigation of function

This new developed knee prosthesis will be compared to the standard scorpio PS knee prosthesis. In this comparison it will be examined if the changes in design really do improve function and deminish pain. Allso patella tracking and patella tilting…

A Phase 3, Multicenter, Randomized Study Comparing CNTO 1275 and Etanercept for the Treatment of Moderate to Severe Plaque Psoriasis

The primary objectives of the study are to compare the efficacy of CNTO1275 to Etanercept and evaluate the safety of CNTO1275 and Etanercept.The secondary objective of this study is to evaluate the efficacy and safety of retreatment with CNTO1275.

Effectiveness of cognitive and graded activity training (COGRAT) on post stroke fatigue. A multi-center study.

Therefore the present study is aimed at answering the following question: does cognitive and graded activity training (COGRAT) lead to a clinically significant reduction of subjective fatigue complaints in stroke patients, when compared with…

A Multi-Center, Single-Blind, Randomized Study Comparing Thymectomy to No Thymectomy in Non-Thymomatous Myasthenia Gravis (MG) Patients Receiving Prednisone

The purpose of this 5-year trial is to determine if the surgical procedure, extended transsternal thymectomy (ETTX), combined with prednisone therapy is more beneficial in treating individuals with non-thymomatous MG than prednisone therapy alone.

Mental Practice embedded in Stroke Rehabilitation: a randomised controlled, multi-centre trial

The overall aim of the proposed research project is to investigate systematically the therapeutic potential of mental practice embedded in daily therapy on the improvement of daily activities of adult stroke patients compared to therapy as usual…

The effect of treatment of craniomandibular dysfunctions(CMD) in patients with long term neck complains;
A single blind randomized, controlled multicentral trial.

Recording if treatment of the craniomandibular region influences the sample of patients with long term neck complaints.

Is metabole regulation of diabetes type 2 patients starting with insuline therapy improved by self-management training? An investigation into decreasing psychological barriers and exploration of etnical barriers.

The objectives of the present study are twofold:1 screening patients with diabetes type 2 for psychological risk factors and2 studying the effect of a self-management training on metabolic regulation in patients starting with insuline therapy

Effect of high-frequency chest wall oscillation and manual hyperinflation on the resolution of atelectasis in ventilated patients

Studies provide statistically significant evidence of the effectiveness of high-frequency chest wall oscillation administered via The Vest* System.St. Elisabeth Ziekenhuis Tilburg wants to demonstrate the effectiveness of HFCWO on ventilator-…

Randomised controlled clinical trial with GRAFTJACKET® , arthroscopic, soft-tissue interposition arthroplasty as a treatment of glenohumeral osteoarthritis.

The primary aim of the study is the prospective recording and follow-up of the clinical and radiographic data of patients who received soft tissue interpositional arthroplasty with Graft Jacket® as a treatment of painful glenohumeral osteoarthritis…

A Randomized multicenter clinical trial of Unruptured Brain AVMs

Primary: To determine whether medical management improves long-term outcomes of patients with unruptured BAVMs compared to invasive therapy (with endovascular procedures, neurosurgery, or radiotherapy, alone or in ombination). The trial has been…

Treatment of recurrent Clostridium difficile infection with fecal therapy:
the FECAL trial (Fecal enema to Eliminate Clostridium difficile Associated Longstanding diarrhea)

With this study we will investiagate the superiority of fecal clysma therapy (n=34 patients) above conventional therapy with the antibiotic vancomycin (n=34 patients) or bowellavage with conventional antibiotic therapy (n=34 patients).