Search for a trial

Mindfulness training versus treatment as usual in adults with attention deficit hyperactivity disorder (ADHD)

To examine the (cost)effectiveness of mindfulness versus treatment as usual (TAU) in adults with Attention Deficit Hyperactivity Disorder (ADHD).

Re-integration Study Xentix

To reduce stress-related problems and increases reintegration of work, the company Letec developed a technique that utilizes the light therapy / magnetic therapy treatment platform Xentix besides coaching. In order to demonstrate the effectiveness…

A Multicenter randomized trial, comparing a 25G EUS Fine Needle Aspiration (FNA) device with a 20G EUS ProCore Fine Needle Biopsy (FNB) device

To compare the performance and diagnostic accuracy of two EUS-guided tissue acquisition devices; a 25G Echotip Ultra Fine Needle Aspiration (FNA) device and a new, more flexible, 20G Echotip ProCore Fine Needle Biopsy (FNB) device.

Comparison of Pure Epicatechin and Cocoa on Markers of Vascular Function

The FLAVO-II study will be conducted as a three-armed, randomized, cross-over intervention trial aimed at comparing the effects of chocolate and pure epicatechin on vascular function.

PVAI alone vs. PVAI plus ablation of complex fractionated atrial electrograms in a specific area of the left atrium in patients suffering from (longstanding) persistent atrial fibrillation.

The aim of this study is to determine if adding ablation restricted to specific areas of the left atrium to PVAI is superior to the standard care PVAI alone.

Mini-internet training in positive reappraisal and concrete thinking for adolescents

This study aims to compare the effects of a training in concrete thinking and a training in positive reappraisal with a control conditions (no specific training instructions) on indices of psychological wellbeing in youth aged 15 to 18. Participants…

The effects of music therapy on expressive and communicative skills in relation to change in behavioral problems for patients with Huntington's Disease

Research questions:1. Does music therapy improve the expressive and communicative skills of patients with HD due to (specific) music therapy treatment? 2. Does music therapy change problem behavior of patients with HD?

Changes in incretines and bile acids after Roux-en-Y Gastric Bypass.

1. comparison between pre- and postoperative serum levels incretines and bile acids (after RYGB).2. comparison between S-RYGB and LBPL-RYGB with respect to incretines and bile acids.

Cognitive remediation in psychiatric patients with an applied online cognitive game and assessment tool

The primary objective of this study is to investigate in a randomized controlled trial (RCT) if AquaSnap can improve cognitive functioning in patients with DSM-IV-TR diagnosis of schizophrenia/schizoaffective disorder, OCD or MDD who have cognitive…

The effects of hyperoxia on organ dysfunction and outcome in critically ill patients with SIRS

1. To study the short- and long-term effect of different target PaO2's on circulatory status, organ dysfunction and outcome.2. To study underlying mechanisms of hyperoxia by determining differences in oxidative stress response between the…

Paediatric pelvic physiotherapy added to conventional treatment of functional constipation in children in primary care.

The primary objective is to study the effect of paediatric pelvic physiotherapy in addition to conventional therapy on the number of patients with treatment success in children aged 4-17 years presenting in primary care with functional constipation…

A randomised comparison of Eye Movement Desensitization and Reprocessing (EMDR), Narrative Exposure Therapy (KIDNET) and waiting list control in traumatized refugee children.

The study aims to answer the following research questions:1. How high/low are levels of symptomatology of depression and/or PTSD in traumatised refugee children in ASC?2. Do symptom levels decrease after a short-term trauma-focused intervention?3.…

The effect of uterine bathing on implantation in endometriosis patients undergoing IVF/ICSI: a randomized controlled pilot trial

To evaluate the effect of uterine bathing in improving the results of IVF/ICSI treatment in patients with endometriosis ASRM stage I-IV.

Effect of restrictive Extended Pouch in Roux-en-Y Gastric Bypass: a prospective randomized control trial

To investigate the effect of variations in the pouch shape and size in RYGB on weightreduction.

Cognitive rehabilitation in brain tumor patients after neurosurgery

The purpose of the proposed project is to evaluate the immediate and long-term effects of cognitive rehabilitation in a prospective randomized trial on neuropsychological test performance and self-reported cognitive symptoms, psychological symptoms…

Mindfulness-Based Cognitive Therapy (MBCT) and Cognitive Behavioral Therapy (CBT) for Depression in Patients after Cancer: a randomized controlled trial

Primary Objective- To assess short and long-term effects of individual Cognitive Behavioral Therapy (CBT) and individual Mindfulness-Based Cognitive Therapy (MBCT) in reducing depressive symptoms in cancer patients with clinically significant…

Effectiveness of Cognitive Remediation Training (CRT) and vocational rehabilitation (IPS), in persons with early psychosis.

The present study focusses especially on the value of cognitive skill training within a program of work integration by means of IPS. Research shows that these interventions indeed lead to enhanced cognitive skills (Wykes et al. 2011). According to…

Reducing symptoms of depression and anxiety in adolescents with inflammatory bowel disease in order to improve quality of life and the clinical course of disease

The primary objective is to determine the efficacy of a disease specific cognitive behavioral therapy program in adolescents with IBD and increased symptoms of depression or anxiety on reducing symptoms of depression. Secondary objectives are to…

A group version of Community Reinforcement and Family Training (CRAFT) compared to Self-Directed Delivery and to non-intervention: a three-armed Randomized Clinical Trial.

In this research the effectiveness of CRAFT Group Traning and CRAFT Bibliotherapy will be examined and outcomes will be compared with no intervention at all.

Can Mild Induced Hypothermia reduce mortality in septic shock patients at the Intensive Care Unit?
A randomized, single-blinded, multicenter study. The cooling and surviving septic shock study

To investigate whether cooling to 33 °C for 24 hours in septic shock reduces mortality in intensive care patients.