154 results
Primary objective: to study the (cost) effectiveness of double layer closure of the uterine scar after a caesarean delivery, in comparison to single layer closure, in the prevention of niche development and related menstrual spotting.Secondary…
Part 1: Main objective: Investigate the relation between level of physical (in)activity and cognition in healthy elderly and to examine the possible moderating effects of (Apolipoprotein E e4) APOEe4 status and IGF-1 and BDNF levels and blood…
Primary Objective: To evaluate the effects of LRYGB with subtotal gastrectomy (LRYGB+) as compared to standard LRYGB (LRYGB-) on striatal D2/D3 receptor availability and dopamine release as well as on whole brain serotonergic activity. Secondary…
This protocol will provide data to comply with regulatory requirements as well as gain substantial additional information on patients in a real world setting. This protocol will compare clinical outcomes of the MISTENT and XIENCE in a broad patient…
To compare the recurrence rate of tumor at 12 months following IMAGE1 S* assisted TURB (Arm A) with White Light Imaging only assisted TURB (Arm B) in patients with primary or recurrent non-muscle-invasive urothelial bladder cancer (NMIBC Ta/T1/CIS…
To study the efficacy of end-ischemic DHOPE in reducing the incidence of NAS within six months after controlled DCD (Maastricht category III) liver transplantation.
To examine whether providing feedback to patients immediately after scoring in a non-valid range on a SVT would have an impact on subsequent symptom validity and neuropsychological test performance. Furthermore, we examine treatment-outcome as a…
This study aims to investigate the effect of switching from Atripla® to Eviplera® on neurocognitive performances (neurocognitive testing) and imaging (functional MRI scanning) in virologically suppressed HIV-infected patients and stable on atripla.
The primary objective is to test the effects of temstem on distress, disturbance to life and social functioning. Second, we aim to investigate the effect of temstem on frequency and severity of AVH, to determine working mechanisms, to identify…
The objective of this study is to examine whether EMDR with flashforward targets can be effective in reducing anxiety related to the future in MS patients. Specifically, following hypotheses will be examined: EMDR with flashforward target…
We are interested to see whether a sulforaphane enriched diet will improve post-operative recovery in healthy patients who donate a kidney for the purpose of a kidney transplantation.
The primary aim of this study was to compare bloodless surgery using vascular clamps and a tourniquet with respect to the development of an anatomical or hemodynamic significant stenosis in patients with a brachiocephalic or radiocephalic AVF.
The aim of this study is to demonstrate that procedural sedation with propofol and esketamine is more effective and will result in less cardiopulmonary depression than sedation with propofol and the opioid alfentanil. Less side effects should also…
To examine the effectiveness of custom made orthotic insoles by a podiatrist, compared to sham orthotic insoles and education alone in patients with plantar fasciitis in terms of pain, function and recovery.
We aim to study the use of braces for thoracolumbar burstfractures, not only by measuring the functional scores and the effect of the bracing or functional treatment on the increase in kyphosis angle, but also on (health related) quality of life and…
Primary objective:1) Does individually tailored robotic gait training with the LOPES II result in more reduction of mechanical work during walking and more improvement of gait symmetry than conventional gait training (of similar frequency and…
This trial aims to study the effects, costs and cost-effectiveness of an App-based program for women 18 years or older withurinary incontinence (UI) in primary care compared to care delivered by the general practitioner (GP) according to the…
The aim of this study is to compare gut-directed hypnotherapy with standard medical treatment in children and adolescents with chronic idiopathic nausea or nausea due to functional dyspepsia. We will examine the effect of these treatments on…
In this randomized, single blinded controlled trial, we evaluate the role of ketamine as an analgesic component of procedural sedation. We compare the effects of propofol-ketamine versus propofol-alfentanil and propofol-remifentanil for achieving a…
Delegation of clozapine monitoring tasks to a Nurse Practitioner (condition A) is at least as safe as Treatment As Usual: physicians perform monitoring tasks themselves (condition B).