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Corrective osteotomy with virtual planning of malunited forearm fractures with and without the use of patient specific guides: a randomized controlled trial

With this study we try to answer the following question:What is the clinical outcome after a corrective osteotomy of a forearm malunion when we virtually plan the correction preoperatively and whether or not use patient-specific guides…

StayFine: a personalized monitoring and intervention app to prevent relapse of anxiety and mood disorders in youth and young adults

To prevent or postpone relapse of anxiety and depression in youth and young adults, with StayFine; a guided app-based modular intervention. Secondary objectives are to explore the effect on other relevant outcomes and to study potential moderators…

Growing up with the Young Endocrine Support System (YESS!): innovative e-technology to improve transition from paediatric to adult care.

Primary Objective: -To investigate whether there is a difference in the Self-management and Transition to Adulthood with Rx (treatment) (STARx) questionnaire score at t=12 months minus the score at t=0 in group YT compared to group O.Secondary…

Trauma-focused Therapies for Posttraumatic stress In Psychosis:
the RE.PROCESS randomised controlled trial

Our primary objective is to test the effects on researcher-rated severity of PTSD symptoms of a full dose of prolonged exposure therapy (PE), eye movement desensitization and reprocessing therapy (EMDR), cognitive restructuring therapy without…

Adalimumab dose reduction aiming low serum concentration with control of disease activity (ADDORA-LOW) : a single blind, non-inferiority, randomised clinical trial

Primary objective: to evaluate the disease activity after dose reduction, aiming adalimumab concentration of 2 mg/L or 5 mg/L, in rheumatoid arthritis patients responding to adalimumab.Secondary objectives: to evaluate whether reducing adalimumab…