134 results
In the current study we will attempt to evaluate if the diet, termed the UC Diet (UCD), can improve outcomes when administered with a 5ASA regimen to pediatric patients with mild-moderate UC, through a single blinded multinational RCT.
This study has been transitioned to CTIS with ID 2024-518769-80-00 check the CTIS register for the current data. Objective 1: to conduct a pragmatic single blind randomised superiority trial (RCT) testing the following hypotheses:1. social recovery…
The proposed study aims to examine the efficacy and process of an individualized (vs. standardized), comprehensive and family-centered neuropsychological intervention for pediatric brain tumor patients experiencing neuropsychological problems. The…
The aim of this research project is to assess the feasibility and acceptability of an adapted version of Group Interpersonal Therapy [IPT] for parents from refugee backgrounds in primary care in The Netherlands. Moreover, the potential effectiveness…
To examine the effect of adrenergic inhibition on the hypoglycaemia induced inflammatory response (e.g. leukocyte phenotype, cytokines, inflammatory proteins) by performing a hyperinsulinaemic hypoglycaemic glucose clamp alongside infusion of α-ARA…
To understand if handsewn (end to end and Kono S side to side) anastomoses is superior to side to side stapled anastomosis after ileocolic resection for Crohn's disease with respect to endoscopic recurrence, gastrointestinal function and costs.
The main objective of this study is to investigate the acute beneficial effect of moderate inten-sive exercise (defined as walking) on neurocognitive functioning in healthy children and adults with mild CP, GMFCS I and II and if this effect is…
Objective of the validation study is evaluating the optimal imaging modality, diffusion tensor magnetic resonance imaging (DT-MRI) or ultrasound, for measuring pennation angle and fascicle length, muscle thickness, muscle volume and cross sectional…
Primary objective: to evaluate the disease activity after dose reduction, aiming adalimumab concentration of 2 mg/L or 5 mg/L, in rheumatoid arthritis patients responding to adalimumab.Secondary objectives: to evaluate whether reducing adalimumab…
The aim of the study is to investigate the effectiveness of a brief manipulation aimed at improving the body image of adolescents with an eating disorder.
the primary aim is to determine the effect of thawed deep-frozen platelets re-suspended in thawed deep-frozen plasma versus room temperature stored platelets in platelet additive solution for transfusion on the percentage of patients with surgical…
The general aim of this project is to better understand the mechanisms involved in safety learning, specifically in adolescents with and without clinical anxiety. First, we aim to investigate differences in vicarious and non-vicarious safety…
Primary- Does the application of Virtual Reality (VR) reduce anxiety in patients undergoing treatment for traumatic injury in the emergency department compared to patients not using VR headset? Secondary- Does the use of Virtual Reality (VR) lead to…
The main objective is to assess the perceived sound quality of different speech and music excerpts that are modified using the dereverberation algorithm by CI users. To this end a suitable graphical user interface (GUI), the MuSHRA, will be…
The two objectives of this study are: 1) validation of two questionnaires, the Misophonia Screening List - Child and Youth and the Amsterdam Misophonia Scale-Youth (AMISOS-Y) in order to screen adequately for misophonia2) testing the effectiveness…
This study aims to investigate the effectiveness of EMDR (n=32) in comparison to a waiting list in (n=32) adolescents (12-18 years) with a primary diagnosis of MDD (DSM-5; American Psychiatric Association, 2013). It is hypothesized that the…
The main aim of the current study is to evaluate the effectiveness of the MVC and FT additives of regular EMDR treatment a) in the therapeutic context and b) with the use of VR-based EMDR in the own living environment of children and adolescents…
The main objective is whether the standard use of non-sterile gloves and/or drapes can be a safe and a good alternative in dento-alveolar surgery. The second objective is to determine whether the use of non-sterile gloves or covering materials is…
This project aims to investigate peripheral and central neuroplasticity following an early (<13 weeks after injury) and intensive (8 weeks of 6 hours of additional therapy) upper extremity motor training program (EIUMT) aimed at recovery…
The current study investigates the effectiveness of an intervention that focusses on the adaptive emotion regulation strategy cognitive reappraisal for people with EDs in the reduction of anxiety. This intervention will be compared to a control task…