2921 results
In this study, the following questions will be answered:1. Does larval therapy accelerate wound healing?2. Do single larval secretions accelerate wound healing?3. Is the bacterial load in the wound reduced during larval therapy or is the microbiome…
The aim of this study is to investigate the effectiveness of a brief computer intervention to improve body satisfcation and self-esteem in a clinical population of adolescents with an eating disorder. We will examine whether the intervention is…
The goal of this clinical investigation is to assess the early migration and bone remodeling of the Symax hip stem and the Trident HA coated or Trident Tritanium acetabulum component with RSA and 18-F PET CT Also the sensitivity of the RSA…
Primary objectives: Evaluation of the efficacy of imiquimod 5% cream compared to treatment with Large Loop excision of the transformation zone (LLETZ) for recurrent/residual CIN.Secondary objectives: evaluation of the effect of treatments on HPV DNA…
The UPGRADE-RT trial will investigate whether de-escalation of the elective radiation dose and introduction of an intermediate dose-level in the treatment of head and neck cancer will results in less radiation sequelae and improved quality of life…
To investigate the effect of variations in the pouch shape and size in RYGB on weightreduction.
The purpose of the proposed project is to evaluate the immediate and long-term effects of cognitive rehabilitation in a prospective randomized trial on neuropsychological test performance and self-reported cognitive symptoms, psychological symptoms…
The primary objective is to determine the safety and tolerability BCG vaccination followed by controlled human malaria infection; and to determine the protective efficacy BCG vaccination against a controlled human malaria infection.
To determine the mechanisms underlying motor skill training, somatosensory electrical stimulation, and a combined intervention on motor skill acquisition, motor memory consolidation, and interlimb transfer in healthy younger and older adults.
To assess the clinical and cost effectiveness of the anterior approach, compared to the conventional posterolateral approach for THA in terms of physical functioning and health-related quality of life
The current study investigates whether the ASPI-score is sensitive to context in which the ASPI is administered. Because the ASPI was designed to measure the capacity to experience sexual pleasure, it is expected that the ASPI score will not vary…
The main objective is to improve predictability of orthognatic surgery, or in other words to realise a stronger relation between (3D virtual) pre-operative planning and post-operative result. The second objective is to evaluate the surgeon*s…
The primary objective of this study is to assess the efficacy of the use of motivational interviewing to improve adherence to wearing prescribed footwear in diabetic foot patients. Secondary objectives are to assess the feasibility of applying…
A prospective randomized phase III clinical trial to study the effectiveness of pathogen-reduced platelet concentrates in plasma, stored for up to 7 days, and compare these with untrested platelet concentrates in plasma, stored for up to 7 days. The…
The first objective of this study is to gain insight in which neurocognitive and neurobiological processes underlie the development of externalizing behavior (in specific aggressive behavior) in the first two years of life. The second objective is…
The main objective is to compare the coronal Cobb angle correction of proximal hook claw fixation versus proximal pedicle screw fixation after two years of follow-up. The secondary objectives of the study are: comparison of coronal Cobb angle…
The primary objective is to test the hypothesis that a protein-rich nutritional supplement (containing 45 g of dietary protein) prior to surgery acutely increases skeletal muscle and bone protein synthesis rates in older patients undergoing a hip…
The purpose of the present study is to investigate the effects of light therapy (with two different light boxes) on depression in people with intellectual disability (IQ *70 ) compared to standard care (care as usual).
To study the effectiveness of gut-directed hypnotherapy in the treatment of IBS-like symptoms in patients with inflammatory bowel disease.
The primary objectives are (1) to investigate the feasibility of online courses targeting nutrition and food-related behaviour and (2) to investigate whether the feasibility of the online courses is related to depressive symptoms. The secondary…