2921 results
Primary objective of this study is to investigate if the Metacognitive Reflection and Insight Therapy (MERIT) improves metacognitive abilities in people with schizophrenia. Secondary objective is to examine whether improvement in metacognitive…
Primary objective: Can application of diagnostic ultrasound and microbubbles enhance epicardial coronary recanalization with a lower and safer dose of a thrombolytic agent such as alteplase 50mg when combined with normal care consisting of prasugrel…
To define the optimum laparoscopic anti-reflux operation, ensuring long-term reflux control with minimal postoperative dysphagia and gas-related symptoms.
Purpose of project-We want to develop, implement and evaluate an 8-session meaning-centered group psychotherapy for Dutch cancer patients, on the basis of Breitbart's intervention, entitled 'Group Training Living Meaningfully with Cancer…
1. To study the effect of different target PaO2's on myocardial damage, hemodynamics, microcirculation and organ perfusion in CABG patients.2. To study underlying mechanisms of hyperoxia by determining differences in oxidative stress response…
Primary Objective: the objective of this study is to determine whether the application topical TA into the pericardial cavity just before sternal closure reduces the 12 hours post-operative blood loss by 25% after cardiac surgery patients on…
The objective of the proposed study is to determine the impact of VRT, in comparison with conventional drug-eluting stenting, on endothelium dependent vasodilation and maximal hyperemic myocardial perfusion using H215O PET.
End-of-life care involves high costs, but frequently fails in providing optimal patient centred care and quality of life. In the US, Advance Care Planning (ACP), a formalised process of communication about care preferences, has resulted in better…
Objective: The primary objective is to evaluate whether distal LRYGB (DLRYGB) is superior in terms of %EWL after one year follow-up compared to standard LRYGB (LRYGB). Secondary objectives are to evaluate effect on quality-of-life (QOL), cure /…
In this RCT we combine cognitive behavioural therapy (CBT) with a maintenance contract and a specific diet (very low calorie diet), to obtain and maintain favourable effects on weight and risk profile over the long term.
The online tailored advice is providing adolescents relevant insight in the negative G-scheme (based on RET). This negative G-scheme leads to inadequate coping strategies. The intervention teaches victims to replace negative irrational beliefs into…
Primary Objective: Can an e-Health application, based on objective measurements, maintain the daily physical activity of COPD patients after a period of rehabilitation?Secondary Objective(s): • Are COPD patients motivated to use the e-Health…
To study the effectiveness of gut-directed hypnotherapy in the treatment of IBS-like symptoms in patients with inflammatory bowel disease.
To investigate the effectiveness of an internet physical activity / self-management program (artroseinbeweging.nl).
1. To quantify the influence of propofol on the distribution, redistribution and elimination of ketamine and to evaluate the importance of hemodynamic parameters on the pharmacokinetics of ketamine.2. To quantify the influence of ketamine on the…
To obtain more information about the effects of capsaicin and cinnamaldehyde on the intestine, these substances will be infused directly in the duodenum. Hereafter, the permeability of the intestine, gallbladder motility and the effects on satiety…
To compare the efficacy of playing Tetris to Assessments Only in the reduction of frequency, vividness, and emotional intensity of intrusions in Dutch soldiers exposed to aversive events on deployment in Afghanistan.
The presently proposed study aims to investigate how dairy proteins compare to vegetable protein and carbohydrate sources leads to glucose and insulin metabolism and substrate partitioning.
Our primary objective is to provide a model which accounts for the inconsistencies in the pharmacological literature regarding the role of the noradrenergic and cholinergic system in visuo-spatial attention. Recently we started a University Medical…
To optimize independent functioning and quality of life through:1. Systematic screening for increased risk of functional loss among community dwelling elderly (Phase 1);2. Providing a nurse-led, complex intervention to elderly people with an…