2921 results
This trial is intended to evaluate the safety and effectiveness of St. Jude Medical*s AMPLATZERTM AmuletTM device (Amulet) in patients with non-valvular atrial fibrillation who are at increased risk for stroke and systemic embolism. The trial will…
To investigate if the use of different stimulation protocols / GnRH-analogues affects embryo developmental kinetics after IVF treatment. We hypothesize that GnRH analogues differentially affect embryo development through differences in follicular…
To compare the recurrence rate of tumor at 12 months following IMAGE1 S* assisted TURB (Arm A) with White Light Imaging only assisted TURB (Arm B) in patients with primary or recurrent non-muscle-invasive urothelial bladder cancer (NMIBC Ta/T1/CIS…
To compare pain relief after PV with a sham intervention in selected patients with a chronic osteoporotic VCF ( three months or longer) using the same strict inclusion criteria as in VERTOS II an IV. Secondary outcome measures are back pain related…
PRIMARY* To demonstrate the non-inferiority of intravenous-to-oral antibiotic switch therapy in clinically stable neonates with probable bacterial infection compared to a complete course of intravenous antibiotic therapySECONDARY* To describe the…
Primary Objective: To compare the composition and functionality of neonatal microbiome arising from mothers receiving antibiotic prophylaxis before skin incision with the microbiome of neonates born when antibiotics are given after umbilical cord…
To assess the effectiveness of perforation and different injection therapies (autologous blood and dextrose) in the treatment of Lateral Epicondylitis of the elbow. The primary objective of our study is examining the change in pain score in the…
To examine whether providing feedback to patients immediately after scoring in a non-valid range on a SVT would have an impact on subsequent symptom validity and neuropsychological test performance. Furthermore, we examine treatment-outcome as a…
The primary objectives of this multicenter randomized clinical trial (RCT) are threefold1. to investigate whether a structured assessment and treatment program of intensive, supervised post partum pelvic floor muscle group training (PFMGT) including…
The objective of the study is to I. study the effectiveness of a standardized EMDR protocol for children with elevated PTSD symptoms (so-called subclinical/partial PTSD) with medically related trauma, and II. To identify factors predicting treatment…
The primary objective is to investigate whether adding a brief mild psychosocial stressor (socially-evaluated cold pressor test) immediately prior to an experimental analogue traumatic event (trauma film paradigm) increases acute endocrine stress…
To quantitate the difference in digestion and absorption kinetics of dietary whole protein versus free amino acids in vivo in patients admitted to the ICU suffering from malabsorption.
There are three aims in this project: 1. To investigate how the functional interaction between the locus coeruleus and other brain areas, in particular the medial temporal lobe areas, during memory processes (encoding, consolidation and retrieval)…
Primary objective: to study the (cost) effectiveness of double layer closure of the uterine scar after a caesarean delivery, in comparison to single layer closure, in the prevention of niche development and related menstrual spotting.Secondary…
1) The BioNIR is non-inferior to the Resolute for the primary clinical endpoint of target lesion failure (TLF) (defined as the composite of cardiac death, target vessel-related MI, or ischemia-driven TLR) at 12 months2/ The BioNIR is non-inferior to…
Primary Objective: The hypothesis of this study is that an Obwegeser Dal Pont splitting procedure with a well- defined inferior border osteotomy needs less torque to split the mandible than the traditional technique.Secondary Objectives: Using the…
The aim of this study is to examine the effectiveness of a nurse-coordinated Cardiac Care Bridge program consisting of care coordination, cardiovascular risk management and home-based rehabilitation for high-risk cardiac patients of 70 years and…
The aim of this study is therefore to prospectively investigate whether prophylactic synthetic mesh placement reduces the rate of stomal site incisional hernias after stoma closure without increasing (infectious) complications.
Physical ExeRcise Following Esophageal Cancer Treatment (PERFECT) Study: a randomized clinical trial
Primary Objective: - To investigate whether a 12-week exercise intervention increases HRQoL in patients after curatively intended EC surgery compared to a usual care control group.Secondary Objective(s): - To investigate whether a 12-week exercise…
The primary objective of this study is to establish the safety and effectiveness of the WATCHMAN TM Left Atrial Appendage Closure (LAAC) Device including the post-implant medication regimen for subjects with non-valvular atrial fibrillation who are…