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Doxycycline and airway inflammation in COPD
A randomised placebo controlled cross-over trial in patients with GOLD III COPD

To assess the effect of low dose doxycycline on markers of neutrophilic inflammation and proteolytic activity stable GOLD III COPD patients.

Placebo controlled trial to evaluate the effect on pain and function of six months treatment doxycycline in established knee osteoarthritis with an open extension up to two years

To asses the short and long term effect on pain and function and the safety of doxycycline in patients with mild to severe pain due to established knee OA.

Doxycycline for Stabilization of Abdominal Aortic Aneurysms

To test whether 100 mg doxycycline inhibits aneurysm growth

The PHENOSAR trial: Antibiotic treatment of biopsy confirmed phenotypes in sarcoidosis: a proof of concept clinical trial

This study has been transitioned to CTIS with ID 2024-513534-38-00 check the CTIS register for the current data. Investigate whether treatment with azithromycin has an inhibitory effect on the mTOR pathway and/or C. acnes, causing a reduction of the…