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DRD4 genotype as a moderator of L-Dopa intervention effects on parent-related neurocognitive processes, behaviors, and attitudes: A micro-trial of differential susceptibility to pharmacological intervention

The study consists of two phases. In the first phase, we aim to investigate whether the dopamine receptor D4 (DRD4) genotype confers differential susceptibility to the effects of early life stress on empathy and prosocial behavior more generally in…

Dopaminergic modulation of cognition and psychomotor function

To replicate and extend the findings of the recent methylphenidate study in which methylphenidate was found to enhance episodic memory performance; To explore whether this effect of methylphenidate is primarily mediated by its dopaminergic action.

A single dose Levodopa study to balance goal-directed and habitual behavior in schizophrenia

to assess whether a single-dose of levodopa improves cognitive symptoms and balances goal-directed and habitual behavior.

The role of dopamine and oxytocin in individual and social performance monitoring

The aim of this study is to improve our understanding of the mechanisms underlying altered social performance monitoring from a pharmacological perspective by directly comparing the effects of dopamine and oxytocin on individual and social…

Levodopa in early Parkinson*s disease;LEAP-5Y-study:
Follow-up of the Levodopa in early Parkinson's disease study

To investigate whether early treatment with levodopa has a delayed beneficial effect on PD symptoms and functional health, and improves the ability to (maintain) work, reduces the use of (informal) care, caregiver burden, and costs. Additionally,…